Training Program in Free Radical and Radiation Biology

自由基和放射生物学培训计划

• 批准号: 6844821
• 负责人: LARRY OBERLEY
• 金额: $ 15.19万
• 依托单位: UNIVERSITY OF IOWA
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-07-01 至 2009-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6844821
• 关键词: Training; Program; Free; Radical; Radiation

DESCRIPTION (provided by applicant): The University of Iowa Training Program in Free Radical and Radiation Biology is oriented around six key goals for education in preparation of trainees for a career in free radical and radiation biology: 1) To impart a fundamental understanding of the subject matter of radiation biology, free radical biology, and cancer biology; 2) To provide trainees with the opportunity to achieve proficiency in the radiation biology, free radical biology, and molecular oncology disciplines leading to successful careers in cancer research; 3) To structure research experience for trainees that includes the development of a research proposal, execution of a research project, and evaluation of these results for submission in peer-reviewed publications; 4) To offer trainees experience in learning the necessary knowledge and skills to do collaborative research with faculty in clinical and basic science departments; 5) To provide trainees with critical knowledge of the structure of science and essential skills in both oral and written scientific communication; and 6) To encourage trainees to implement innovative approaches in a "real world" environment to test explicit hypotheses about the mechanisms and consequences of radiobiological and free radical phenomena. With this application, we are proposing to continue to support three predoctoral trainees per year and also to phase in the additional support of postdoctoral trainees. We propose to support one postdoctoral trainee in the first year, two in the second, and three in years 3-5. We have an internationally recognized faculty with consistent involvement in nationally recognized radiobiology and free radical research projects, program projects, individual research awards, and The University of Iowa Cancer Center. We propose to have 10 mentors in the Training Program, 4 from the Department of Radiation Oncology and one each from the Departments of Internal Medicine, Pathology, Surgery, Anatomy and Cell Biology, Exercise Science, and Chemistry. Education for our trainees involves one-on-one mentoring by faculty members, working on cancer related nationally recognized research projects, presenting work and receiving feedback at national meetings, plus formal course work offered by the department and the other excellent resources at The University of Iowa. Formal coursework includes classes in radiation, free radical, and cancer biology. The faculty, fellows, and students form a critical mass for providing a provocative environment for seminars, journal clubs, and informal discussion. Research being pursued goes from the bench top to the clinic. Communication, both verbal and written, is stressed in the Training Program, so that the science that is done can be communicated to other scientists. We believe this Training Program has all the ingredients necessary to produce the needed high quality scientists in free radical and radiation biology who will work in cancer research.

描述（由申请人提供）：爱荷华大学自由基和辐射生物学培训计划围绕六个关键教育目标，为学员在自由基和辐射生物学领域的职业生涯做好准备： 1) 传授对辐射生物学、自由基生物学和癌症生物学主题的基本理解； 2) 为学员​​提供熟练掌握放射生物学、自由基生物学和分子肿瘤学学科的机会，从而在癌症研究领域取得成功的职业生涯； 3) 为学员​​构建研究经验，包括制定研究计划、执行研究项目以及评估这些结果以提交同行评审的出版物； 4）为学员提供学习必要知识和技能的经验，以便与临床和基础科学部门的教师进行合作研究； 5) 为学员​​提供科学结构的批判性知识以及口头和书面科学交流的基本技能；和 6) 鼓励学员在“现实世界”环境中实施创新方法，以测试有关放射生物学和自由基现象的机制和后果的明确假设。 通过此申请，我们建议继续每年支持三名博士前培训生，并分阶段提供对博士后培训生的额外支持。 我们建议第一年支持一名博士后培训生，第二年支持两名，第三年至第五年支持三名。 我们拥有国际认可的教师队伍，一直参与国家认可的放射生物学和自由基研究项目、计划项目、个人研究奖项以及爱荷华大学癌症中心。 我们建议培训项目有 10 名导师，其中 4 名来自放射肿瘤科，内科、病理科、外科、解剖学和细胞生物学、运动科学和化学科各 1 名。 对学员的教育包括教师一对一的指导、从事与癌症相关的国家认可的研究项目、在国家会议上展示工作并接收反馈，以及该系提供的正式课程作业和大学的其他优秀资源。爱荷华州。 正式课程包括辐射、自由基和癌症生物学课程。 教师、研究员和学生构成了为研讨会、期刊俱乐部和非正式讨论提供激发性环境的关键群体。 正在进行的研究从实验室到临床。 培训计划强调口头和书面交流，以便将完成的科学成果传达给其他科学家。 我们相信，该培训计划具备培养自由基和辐射生物学领域所需的高素质科学家所需的所有要素，他们将从事癌症研究。