BRAIN SYSTEMS FOR REGULATING RESPONSES TO COGNITIVE AND AFFECTIVE CONFLICT

调节认知和情感冲突反应的大脑系统

• 批准号: 7203175
• 负责人: DIANE SWICK
• 金额: $ 0.3万
• 依托单位: UNIVERSITY OF CALIFORNIA AT DAVIS
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-04-01 至 2006-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7203175
• 关键词: BRAIN; SYSTEMS; REGULATING; RESPONSES; COGNITIVE

The University of California Davis (UC Davis) in collaboration with the Veterans Affairs Northern California Health Care System (VANCHCS) proposes a General Clinical Research Center to provide a centralized infrastructure to support clinical/translational research and to expand clinical research training and career development programs. UC Davis is well positioned to undertake this ambitious proposal; major resources are already allocated to clinical research as part of a focused five-year plan to create a vibrant and dynamic clinical research community. UC Davis has recruited experienced clinical researchers from a multitude of universities, is currently recruiting a new Assistant Dean for Clinical Research, and the leadership of the school is fully committed to the success of the GCRC. A designated 7,500 square feet GCRC unit is a part of the newly constructed Sacramento VA Medical Center, and VANCHCS and UC Davis have provided resources to develop this facility. UC Davis and the VANCHCS have provided more than $3.5 million to create the GCRC. Of this amount, $2.5 million represent cost for construction of the GCRC facility, and $1 million represents support for the development phase. Thus, the infrastructure for the GCRC is already in place, and GCRC leaders have been identified. The rapid growth in sponsored research at UC Davis together with the strategic focus on clinical and translational research makes the proposed GCRC a necessary and essential component to achieve the ambitious goals of UC Davis and VANCHCS to create a cutting edge clinical research enterprise with a critical mass of investigators. The 63 submitted protocols use inpatient, outpatient, laboratory, biostatistical, nutrition, patient safety and informatics support for patient-oriented research. They represent a wide spectrum of investigators and research areas. Reflecting the scientific strengths at UC Davis, the majority of the protocols have been developed by investigators in four leading, broadly defined and inclusive focus areas; Infectious Disease, Cancer, Vascular Biology/Metabolism, and Neuroscience. These areas have been identified by the UC Davis Health System leadership as principal areas for future research growth. Beyond these areas, the GCRC has fostered campus-wide collaborations with investigators representing basic sciences, all the leading clinical centers, and areas outside the medical school such as nutrition and engineering. We will continue to facilitate and assist clinical researchers from all areas. Mentoring and education plans are a top priority of the GCRC, and will serve as a critical catalyst to expand and focus the many existing resources and initiatives already in place at UC Davis. We aspire to perform patient-oriented research with the highest standards of patient care, ethics, scientific rigor, safety and regulatory compliance, and the GCRC is an essential component to achieve these goals.

加州大学戴维斯分校 (UC Davis) 与退伍军人事务部北加州医疗保健系统 (VANCCHS) 合作提议建立一个综合临床研究中心，以提供集中的基础设施来支持临床/转化研究并扩大临床研究培训和职业发展计划。加州大学戴维斯分校完全有能力承担这项雄心勃勃的提议；作为重点五年计划的一部分，主要资源已分配给临床研究，以创建一个充满活力和活力的临床研究社区。加州大学戴维斯分校已从多所大学招募了经验丰富的临床研究人员，目前正在招募新的临床研究助理院长，学校领导层将全力支持 GCRC 的成功。指定的 7,500 平方英尺 GCRC 单元是新建的萨克拉门托退伍军人医疗中心的一部分，VANCCHS 和加州大学戴维斯分校已 提供了开发该设施的资源。加州大学戴维斯分校和 VANCHCS 已提供超过 350 万美元来创建 GCRC。其中，250 万美元是 GCRC 设施的建设成本，100 万美元是对开发阶段的支持。至此，GCRC 的基础设施已经就位，并且 GCRC 的领导人也已经确定。加州大学戴维斯分校赞助研究的快速增长以及对临床和临床的战略重点 转化研究使拟议的 GCRC 成为实现加州大学戴维斯分校和 VANCHCS 的宏伟目标的必要和重要组成部分，即创建一个拥有大量研究人员的尖端临床研究企业。提交的 63 份方案涉及住院患者、门诊患者、实验室、生物统计、营养、患者安全和信息学 支持以患者为导向的研究。他们代表了广泛的研究人员和研究领域。大多数方案是由研究人员在四个领先、广泛定义和包容性重点领域制定的，反映了加州大学戴维斯分校的科学优势；传染病、癌症、血管生物学/代谢和神经科学。这些领域已被加州大学戴维斯分校卫生系统领导层确定为主要领域 未来的研究增长。除了这些领域之外，GCRC 还促进了校园范围内与代表基础科学的研究人员、所有领先的临床中心以及医学院以外的领域（如营养和工程）的合作。我们将继续为各个领域的临床研究人员提供便利和协助。指导和教育计划是 GCRC 的首要任务，并将成为扩大和集中加州大学戴维斯分校现有资源和举措的关键催化剂。我们渴望以最高标准的患者护理、道德、科学严谨性、安全性和监管合规性开展以患者为导向的研究，而 GCRC 是实现这些目标的重要组成部分。