Prescription Drug Abuse Among Club Drug Users

俱乐部吸毒者中的处方药滥用情况

基本信息

批准号：
6986538
负责人：
JAMES A INCIARDI
金额：
$ 63.03万
依托单位：
UNIVERSITY OF DELAWARE
依托单位国家：
美国
项目类别：
财政年份：
2005
资助国家：
美国
起止时间：
2005-08-01 至 2010-07-31
项目状态：
已结题

项目摘要

DESCRIPTION (provided by applicant): The non-medical use of Pharmaceuticals has been a long-standing problem in the United States, and since the 1970s the use of "club drugs" has been a problem among adolescents and young adults. A recent trend has been the incursion of prescription drugs into the club culture, with the concomitant health consequences associated with their abuse. Because of their young age and their tendency to mix numerous drugs during any given drug binge, club drug users tend to be a highly vulnerable population. Within this context, the specific aims of this application are to; 1) recruit a sample of 750 out-of-treatment prescription and club drugs abusers ages 18-39 and at baseline assess their life histories of alcohol and drug abuse onset and progression, and extent of current alcohol and prescription, club and other drug use; 2) at 6, 12 and 18 months, assess changes in onset, progression, and extent of respondents' alcohol and prescription, club and other drug use; 3) at baseline, 6, 12 months and 18 months, assess the mechanisms of access to prescription drugs among the sampled drug users; 4) at baseline, 6, 12 and 18 months, investigate the impact of quantity, frequency, types and duration of prescription and club drug abuse on the nature and extent of health and social consequences within this population, including: sexual risk-taking and coercion; drug interactions and overdose; chronic drug use; impairment of daily activities; physical problems; mental health problems; and legal problems; and 5) examine the impact of gender and other potential correlates (sexual identity, sexual history, current sexual behaviors, drug history, and current drug use) on onset, progression, and extent of prescription, club and other drug abuse and the nature and extent of health and social consequences. The study sample will reflect the race/ethnic distribution of the Miami population: 30 percent white/Anglo, 50 percent Hispanic, and 20 percent African-American, with a gender distribution of 50 percent female and 50 percent male. A variety of statistical techniques will be used to describe the population, the epidemiology of prescription and other drug use in the club culture, and the nature and prevalence of related consequences. The short-term objectives are to describe the changing nature of prescription drug abuse/club drug use and their consequences in the Miami club culture. A broader long-term goal is to better understand current patterns of the abuse of prescription drugs and their incursion into the club culture, in order that strategies can be developed for reducing the abuse and diversion of these drugs in Miami and other communities. Such strategies and policies may ultimately reduce the abuse and diversion of prescription drugs, as well as make them more readily available to the patients for whom they are intended.

描述（由申请人提供）：药品的非医疗用途在美国一直是一个长期存在的问题，自 20 世纪 70 年代以来，“俱乐部毒品”的使用一直是青少年和年轻人中的一个问题。最近的一个趋势是处方药侵入俱乐部文化，并伴随着滥用处方药带来的健康后果。由于俱乐部吸毒者年龄较小，并且在任何一次吸毒狂潮中都倾向于混合使用多种毒品，因此俱乐部吸毒者往往是高度脆弱的人群。在此背景下，该应用程序的具体目标是： 1) 招募 750 名 18-39 岁、未接受治疗的处方药和俱乐部药物滥用者作为样本，并在基线时评估他们的酒精和药物滥用发作和进展的生活史，以及当前酒精和处方药、俱乐部药物和其他药物使用的程度; 2) 在第 6、12 和 18 个月时，评估受访者酒精、处方药、俱乐部和其他药物使用的发病、进展和程度的变化； 3) 在基线、6个月、12个月和18个月时，评估抽样吸毒者获得处方药的机制； 4) 在基线、第 6、12 和 18 个月，调查处方药和俱乐部药物滥用的数量、频率、类型和持续时间对该人群健康和社会后果的性质和程度的影响，包括：性冒险和强迫;药物相互作用和药物过量；长期吸毒；日常活动受损；身体问题；心理健康问题；和法律问题； 5) 检查性别和其他潜在相关因素（性别认同、性史、当前性行为、吸毒史和当前吸毒情况）对处方药、俱乐部和其他药物滥用的发生、进展和程度的影响以及药物滥用的性质和影响健康和社会后果的程度。研究样本将反映迈阿密人口的种族/民族分布：30% 为白人/盎格鲁人，50% 为西班牙裔，20% 为非洲裔美国人，性别分布为 50% 女性和 50% 男性。将使用各种统计技术来描述人群、俱乐部文化中处方药和其他药物使用的流行病学，以及相关后果的性质和普遍性。短期目标是描述处方药滥用/俱乐部吸毒性质的变化及其对迈阿密俱乐部文化的影响。更广泛的长期目标是更好地了解处方药滥用的当前模式及其对俱乐部文化的侵入，以便制定策略来减少迈阿密和其他社区这些药物的滥用和转移。这些策略和政策最终可能会减少处方药的滥用和转移，并使目标患者更容易获得这些药物。