Community-based Hep B Intervention for Hmong Adults

针对苗族成人的社区乙肝干预

• 批准号: 7102338
• 负责人: Moon Shao-Chuang Chen
• 金额: $ 40.14万
• 依托单位: UNIVERSITY OF CALIFORNIA AT DAVIS
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-04-01 至 2011-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7102338
• 关键词: Asian Americans; behavioral /social science research tag; cancer prevention; clinical trials; communicable disease diagnosis; community health services; education evaluation /planning; health behavior; health care personnel; health disparity; health education; health services research tag; hepatitis B; hepatitis B virus group; human subject; liver neoplasms; medical records; patient oriented research; virus related neoplasm /cancer

Unlike other ethnic groups who attribute their origin to a single country, Hmong Americans originate from the mountainous regions at the confluence of Vietnam, Cambodia, and Laos. The U.S. government resettled Hmong who escaped from Southeast Asia to California and the Midwest. At the time of migration, the Hmong were pre-literate, believed in animism, and were accustomed to an agrarian lifestyle. Our latest California data indicate that the age-adjusted male incidence rate for liver cancer for Hmong is 25.7/100,000 compared to 3.7/100,000 for non-Hispanic white males and 8.8/100,000 for female Hmong compared to 1.5/100,000 in non-Hispanic White females. The purpose of this study is to increase the hepatitis B serological testing for Hmong adults and secondarily to increase their knowledge levels of hepatitis B and liver cancer. Over the five year research tudy, we propose to: (1) measure the baseline proportion seroloically tested for hepatitis B [HBV] among Hmong, ages 18-64, in the Greater Sacramento Area; (2) Develop an intervention using lay health workers to promote serological testing for HBV and increase knowledge of HBV among Hmong adults; (3) Evaluate the effectiveness of the lay health worker intervention by conducting a randomized, controlled trial among Hmong adults aged 18-64 not previously tested for HBV; and (4) Characterize facilitating and impeding factors associated with serological testing for HBV among Hmong adults. To achieve these Aims, universitybased researchers will work collaboratively with Hmong bilingual interviewers, community leaders, and agencies in conducting a baseline assessment of serological testing among Hmong and follow with randomizing those who have not been serologically tested for HBV into intervention or control conditions. We shall use the Health Behavior Framework to guide our study and the lay health worker teams as the intervention agents . Intervention effectiveness will be based on the basis of self-reported serological testing rates that will be also verified through medical records check. We have detailed the training and evaluation of lay health workers and have incorporated rigorous safeguards to minimize contamination. As a consequence of this study, we expect data on the empirical effectiveness of a lay health worker intervention model for increasing serological testing for HBV and that the burden of HBV-induced liver cancer reduced.

与其他将自己的起源归于单一国家的民族不同，苗族美国人起源于 越南、柬埔寨、老挝交界处的山区。美国政府重新安置 苗族人从东南亚逃到加利福尼亚和中西部。迁移时， 苗族没有识字，相信万物有灵论，习惯于农业生活方式。我们最新的 加州数据显示，苗族男性肝癌发病率按年龄调整为 25.7/100,000 相比之下，非西班牙裔白人男性为 3.7/100,000，苗族女性为 8.8/100,000 非西班牙裔白人女性中为 1.5/100,000。 本研究的目的是增加苗族成年人和苗族的乙型肝炎血清学检测 其次提高乙型肝炎和肝癌的知识水平。经过五年的研究 研究中，我们建议：(1) 测量接受乙型肝炎 [HBV] 血清学检测的基线比例 苗族，年龄 18-64 岁，居住在大萨克拉门托地区； (2) 利用非专业卫生工作者制定干预措施 促进乙肝病毒血清学检测并提高苗族成年人对乙肝病毒的了解； (3) 评估 通过对非专业卫生工作者进行随机对照试验来评估其干预的有效性 18-64 岁的苗族成年人以前未接受过乙肝病毒检测； (4) 描述促进和阻碍的特征 与苗族成人乙型肝炎病毒血清学检测相关的因素。为了实现这些目标，以大学为基础 研究人员将与苗族双语访谈员、社区领袖和 各机构对苗族血清学检测进行基线评估，并遵循 将那些未接受乙型肝炎血清学检测的人随机分为干预组或对照组。 我们将使用健康行为框架来指导我们的研究，并将非专业卫生工作者团队作为 干预剂。干预措施的有效性将基于自我报告的血清学检测 费率也将通过医疗记录检查进行验证。我们有详细的培训和评估 的非专业卫生工作者，并采取严格的保障措施以尽量减少污染。作为一个 这项研究的结果是，我们期望获得有关非专业卫生工作者干预的实证有效性的数据 增加 HBV 血清学检测的模型，并减少 HBV 诱发的肝癌的负担。