Older Americans Independence Center

美国老年人独立中心

• 批准号: 6894246
• 负责人: LINDA P FRIED
• 金额: $ 136.08万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-06-01 至 2008-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6894246
• 关键词: biomedical facility; clinical research; disease /disorder etiology; frail elderly; geriatrics; quality of life

DESCRIPTION (provided by applicant): This proposal seeks to establish an Older Americans Independence Center at the Johns Hopkins Medical Institutions. The focus of this center is to promote independence for frail older adults through the development of interventions to prevent or ameliorate frailty and the many serious, adverse outcomes that frail older adults are at risk for. To accomplish this, a multidisciplinary group of senior and junior investigators, in multiple Departments and Programs at this institution, propose to implement, through this OAIC, 1. the leadership group that will stimulate, lead and sustain a University-wide interdisciplinary research program investigating frailty, its etiology and opportunities for treatment; 2. the infrastructure and methodologic development essential to creating the next generations of research on frailty in older adults; 3. to support the career development of outstanding junior faculty committed to research careers that will lead to treatments for frailty and its prevention; and 4. to cultivate and support pilot studies that will provide the basis for investigator-initiated and funded research on frailty over the long run. The OAIC would provide the support critical to organizing the substantial strengths already at this institution into a unified and potent effort directed at developing interventions for frailty. It is designed to ensure multidisciplinary translation between basic and clinical/population-based research, and of both into development of treatments for frailty. This organized infrastructure and scientific leadership can serve as a source of advice and collaborations to investigators at our own institution and at other institutions in the area of research on frailty in aging. The OAIC will be administratively led by, and housed in, the Johns Hopkins Center on Aging and Health, with strong leadership and participation by all of the institutional programs committed to aging research; it will also incorporate leaders and investigators not previously involved in research on frailty but who have made a commitment to this work through the planning process for this proposal. This OAIC has strong institutional commitment, based on the priority at the Medical Institutions for the unification and strengthening of aging research and spotlighting its importance for the entire institution. Overall, it is designed to spearhead a new depth and intensity of research to improve outcomes and promote independence for frail, older adults.

描述（由申请人提供）：该提案旨在在约翰·霍普金斯医疗机构建立一个年长的美国人独立中心。该中心的重点是通过开发预防或改善脆弱的干预措施来促进脆弱的老年人的独立性，以及脆弱的老年人处于风险中的许多严重，不利的结果。为此，该机构多个部门和计划的高级和初级调查人员组成的跨学科小组建议通过这个OAIC 1。将刺激，领导和维持一项大学范围内的跨学科研究计划，调查脆弱，其病因，其病因和治疗机会； 2。基础设施和方法论发展对于在老年人中创建关于脆弱的下一代研究至关重要； 3。支持致力于研究职业的杰出初级教师的职业发展，这将导致脆弱及其预防的治疗；和4。培养和支持试点研究，从长远来看，将为研究人员发动和资助的脆弱研究提供基础。 OAIC将为将该机构的实质优势组织成统一和有力的努力提供致力于制定脆弱干预措施的统一和有力的努力提供至关重要的支持。它旨在确保基本和基于临床/人群的研究之间的多学科翻译，以及两者之间的脆弱治疗方法。这种有组织的基础设施和科学领导可以作为我们机构的调查人员以及衰老研究研究领域的其他机构的建议和合作的来源。 OAIC将由约翰·霍普金斯（John Hopkins）衰老和健康中心的行政领导和安置，并由致力于老化研究的所有机构计划进行强大的领导和参与；它还将结合以前不参与脆弱研究的领导者和调查人员，而是通过该提案的计划过程对这项工作做出了承诺。基于医疗机构的优先事项，这项OAIC具有强大的机构承诺，以统一和加强衰老研究并关注其对整个机构的重要性。总体而言，它旨在使研究的新深度和强度率先，以改善结局并促进脆弱的老年人独立性。