UHI COBRE: PATHOGENETICS OF RECESSIVE PSEUDOXANTHOMA ELASTICUM

UHI COBRE：隐性弹性假黄瘤的发病机制

• 批准号: 7170544
• 负责人: OLIVIER LE SAUX
• 金额: $ 21.55万
• 依托单位: UNIVERSITY OF HAWAII AT MANOA
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-07-01 至 2006-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7170544
• 关键词: biomedical facility; cardiovascular disorder; cardiovascular function; clinical research; health science research

DESCRIPTION (provided by applicant): The overall goal of this COBRE initiative is to develop a Center for Cardiovascular Research at the University of Hawaii (UH). This proposal is built upon several exciting new developments at the University over the last four years that have made this initiative possible. The biology and particularly the pathobiology of the cardiovascular system has been an emerging research theme at UH. The NIH-funded principal investigators directing these research efforts have established a track record of collaboration and an effective mentoring program for promising young faculty. With funds from this center proposal, these nationally recognized investigators, with expertise in molecular and cell biology, biochemistry and genetics, would have the opportunity, under the direction of the Principal Investigator, to expand upon and enhance their current research and mentoring capabilities. These goals would be achieved through three primary specific aims: 1. The development of a strong mentoring group of established investigators, with interdisciplinary but complementary backgrounds in vascular and cardiovascular biology, to support the career growth of a selected group of promising young investigators. 2. The enhancement of infrastructure support through the development of laboratory core facilities, adminstrative support and resources, in order to increase the research competitiveness of both established investigators and young faculty. 3. The development of a strategic plan to assist in the recruitment and retention of talented and funded young faculty and established investigators in faculty positions at UH in order to promote the continued growth of a cardiovascular research program into a major research discipline at UH with stable funding opportunities to not only parallel but to eventually replace COBRE funding.

描述（由申请人提供）：此毛绒的总体目标 倡议是在建立心血管研究中心 夏威夷大学（UH）。 该提案建立在几个令人兴奋的新事态发展的基础上 在过去的四年中，这项倡议成为可能。 生物学，尤其是心血管系统的病理学 是UH的新兴研究主题。 NIH资助的首席调查员 指导这些研究工作已经建立了 合作和有效的年轻教师的有效指导计划。 通过该中心提议的资金，这些全国认可 研究人员，具有分子和细胞生物学，生物化学和细胞生物学方面的专业知识 遗传学，将有机会在校长的指导下 调查员，扩展并增强他们当前的研究和指导 功能。这些目标将通过三个主要特定特定来实现 目标： 1。建立了强大的研究人员的发展， 具有跨学科但互补背景的血管和互补背景 心血管生物学，以支持选定的一组的职业发展 有前途的年轻调查员。 2。通过发展基础设施支持的增强 实验室核心设施，义务支持和资源，以便 提高既定研究者和 年轻教师。 3。制定战略计划，以协助招募和 保留才华横溢和资助的年轻教师，并成立的调查员 在UH的教师职位上，以促进A的持续增长 在UH的主要研究学科中，心血管研究计划 稳定的资金机会不仅可以平行，而且最终取代 鞋垫资金。