Adaptive Stimulator for Exercise and Rehabilitation

用于运动和康复的自适应刺激器

• 批准号: 7098728
• 负责人: Eric C Hartman
• 金额: $ 40万
• 依托单位: CUSTOMKYNETICS, INC.
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-02-25 至 2009-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7098728
• 关键词: bioengineering /biomedical engineering; biomechanics; biomedical equipment development; biosensor device; body movement; brain injury; clinical research; clinical trials; computer program /software; computer system design /evaluation; electronic stimulator; electrostimulus; exercise; human subject; medical rehabilitation related tag; muscle function; muscle strength; orthopedics; paralysis; patient oriented research; portable biomedical equipment; rehabilitation; spinal cord injury; stroke

DESCRIPTION (provided by applicant): We propose to develop an electrical stimulation system with adaptive capabilities for exercise and rehabilitation. The target populations are: 1) individuals with complete or incomplete SCI who are interested in improving their physical fitness through electrically stimulated lower-extremity exercise, 2) individuals with complete or incomplete SCI who seek to develop or maintain adequate muscle strength to allow routine use of an FES system for standing, and 3) individuals with incomplete spinal cord injury, brain injury, or stroke who have the potential to regain voluntary lower extremity motor function through motor retraining therapy. The proposed portable exercise unit will include sensors and an adaptive control algorithm to provide repeatable movements. We anticipate that the adaptive controller will provide safe and effective exercise and that the adaptive controller will allow the exercise goals to be defined in movement rather than stimulation-specific parameters. For motor retraining, the system will encourage maximum voluntary effort by providing only the stimulation required to supplement the user's effort. The Phase I aims were achieved successfully. Phase I results clearly demonstrate the feasibility of our approach and have laid a strong foundation for the proposed Phase II effort. In Phase II, we will: 1) develop sensors to provide direct knee angle measurements and simplify donning and calibration, 2) develop a prototype adaptive stimulator for use by individuals with complete or incomplete SCI, 3) develop a clinical software suite for protocol programming, performance evaluation, and documentation, 4) assess the efficacy of the device in a study involving individuals with complete injuries who wish to increase muscle mass, strength and endurance through a long-term electrical stimulation based training protocol, and 5) assess the efficacy of the device in a study involving individuals with incomplete injuries who have some degree of voluntary control over the target muscles and who wish to improve muscle condition and potentially improve their ability to perform functional voluntary activities.

描述（由申请人提供）：我们建议开发具有适应性和康复能力的电刺激系统。目标人群是：1）具有完整或不完整的SCI的个体，他们有兴趣通过电刺激的低肢体锻炼来改善其身体健康，2）具有完整或不完整的SCI的个体，他们试图发展或保持肌肉力量，以便常规地使用FES系统，以及3）具有不完全的脊髓损伤的人，可以通过脊髓损伤进行降低或驾驶能力恢复，或者遭受了弱势疗效，并具有恢复性验证，或者遭受了弱点的功能。 提出的便携式运动单元将包括传感器和自适应控制算法，以提供可重复的运动。我们预计自适应控制器将提供安全有效的锻炼，并且自适应控制器将允许在运动中定义运动目标，而不是特定于刺激的参数。对于电机再培训，系统将仅提供补充用户努力所需的刺激来鼓励最大的自愿努力。 I阶段的目标已成功实现。第一阶段的结果清楚地证明了我们方法的可行性，并为拟议的II期努力奠定了坚实的基础。 在第二阶段，我们将：1）开发传感器以提供直接的膝盖角度测量并简化捐赠和校准，2）开发一个原型的适应性刺激器，用于使用完整或不完整的SCI的个人使用，3）为协议计划，绩效评估和文献评估和文档进行临床软件套件，以使YESSERATION和YESTER INSTER INSTER INTER INTER INTER INSTISS与完整的群体相关，4）希望能够涉及一项范围，4）希望能够涉及一项范围，以使其与远远的效率相关，以便在群众中效率，以使群众群体的效率，以便在群众中效率，以使群众群体的效率，以便为群体提供效率，以便为忙碌的忙碌而努力。基于电刺激的训练方案，以及5）评估该设备在一项研究中的功效，该研究涉及对目标肌肉有一定程度自愿控制并希望改善肌肉状况并有可能提高其功能性自愿活动的能力的人。