Ethnicity and Pregnancy Outcomes in New York City

纽约市的种族和怀孕结果

• 批准号: 7140345
• 负责人: David A Savitz
• 金额: $ 19.95万
• 依托单位: ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-07-01 至 2008-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7140345
• 关键词: African American; Asians; Hispanic Americans; Pacific Islander; United States; age difference; caucasian American; clinical research; developmental disease /disorder; education; gestational diabetes mellitus; human data; infant mortality; longitudinal human study; low birth weight infant human; marriage /marital status; outcomes research; preeclampsia; pregnancy disorder; pregnancy loss; pregnancy toxemia /hypertension; premature infant human; racial /ethnic difference; socioeconomics; statistics /biometry; women' s health

DESCRIPTION (provided by applicant): The major ethnic groups in the United States, African-Americans, Latinos, and Asians, show distinctive patterns of pregnancy outcome, including preterm birth, low birth weight, and infant mortality. Numerous reports have described this, but there has been little effort to extend these observations to address possible causal pathways underlying the patterns. In order to extend our understanding of the role of ethnicity and socioeconomic conditions on pregnancy outcome, we propose to analyze births in New York City over the period 1998-2002, a 5-year period straddling the 2000 Census, with over 500,000 births included in the final analysis. Through this combination of data sources, we will: describe ethnic patterns of pregnancy outcome, including preterm birth, growth restriction, and common pregnancy complications, characterize risk factors among women of varying ethnicity, including sociodemographic characteristics such as age, marital status, and education, and a number of medical conditions affecting the outcome of pregnancy. Measures of ethnicity at the individual level include race, Hispanic ethnicity, nativity, and ancestry, and we will be able to identify and analyze refined subgroups (e.g., Puerto Ricans, Asian Indians, Koreans) given the size and diversity of the New York City population. We will conduct a multi-level statistical analysis that takes into account both individual attributes from the birth certificate and neighborhood features from the US Census to examine their separate and joint effects, focusing on the influence of ethnicity, socioeconomic status, nativity, and concentration of ethnicity within Census Tracts. By elucidating the relationship between ethnicity and pregnancy outcome more fully, considering a broader range of ethnicities defined in greater detail, and integrating individual and community level socioeconomic influences, we will be better able to target groups in need of intervention as well as identify clues to etiology.

描述（由申请人提供）：美国，非裔美国人，拉丁裔和亚洲人的主要种族群体显示出独特的怀孕结果模式，包括早产，低出生体重和婴儿死亡率。许多报道已经描述了这一点，但是很少努力扩展这些观察结果，以解决模式基础的可能因果途径。为了扩展我们对种族和社会经济状况对怀孕结局的作用的理解，我们建议在1998 - 2002年期间分析纽约市的出生，这是跨越2000年人口普查的5年期，最终分析中包含超过500,000个出生。通过这种数据源的结合，我们将：描述妊娠结局的种族模式，包括早产，生长限制和常见的怀孕并发症，表征不同种族的妇女的危险因素，包括社会人口统计学特征，例如年龄，婚姻状况和教育以及影响怀孕结果的许多医疗状况。个人层面的种族措施包括种族，西班牙裔种族，耶稣诞生和祖先，我们将能够鉴于纽约市人口的规模和多样性，我们将能够识别和分析精致的亚组（例如波多黎各人，亚洲印第安人，韩国人）。我们将进行多层统计分析，该分析考虑了来自美国人口普查的出生证明书和邻里特征的两个个人属性，以检查其独立的和关节影响，重点是人口普查区内种族，社会经济地位，诞生和族裔集中的影响。通过考虑更详细定义的更广泛的种族以及整合个人和社区层面的社会经济影响，我们将更好地阐明种族与怀孕结局之间的关系，我们将更好地针对需要干预的群体以及确定病因的线索。

项目成果

Decline in smoking during pregnancy in New York City, 1995-2005.

1995-2005 年纽约市怀孕期间吸烟率下降。

• DOI: 10.1177/003335490912400612
• 发表时间: 2009
• 期刊: Public health reports (Washington, D.C. : 1974)
• 作者: Stein,CherylR;Ellis,JenniferA;Savitz,DavidA;Vichinsky,Laura;Perl,SarahB
• 通讯作者: Perl,SarahB

Assessing variance components in multilevel linear models using approximate Bayes factors: A case study of ethnic disparities in birthweight.

使用近似贝叶斯因子评估多级线性模型中的方差分量：出生体重种族差异的案例研究。

• DOI: 10.1111/j.1467-985x.2011.00685.x
• 发表时间: 2011
• 期刊: Journal of the Royal Statistical Society. Series A, (Statistics in Society)
• 作者: Saville,BenjaminR;Herring,AmyH;Kaufman,JayS
• 通讯作者: Kaufman,JayS

Gestational weight gain and birth outcome in relation to prepregnancy body mass index and ethnicity.

• DOI: 10.1016/j.annepidem.2010.06.009
• 发表时间: 2011-02
• 期刊: ANNALS OF EPIDEMIOLOGY
• 影响因子: 5.6
• 作者: Savitz, David A.;Stein, Cheryl R.;Siega-Riz, Anna Maria;Herring, Amy H.
• 通讯作者: Herring, Amy H.

Screening young adults for prevalent chlamydial infection in community settings.

在社区环境中筛查年轻人是否存在流行的衣原体感染。

• DOI: 10.1016/j.annepidem.2008.03.002
• 发表时间: 2008
• 期刊: Annals of epidemiology
• 影响因子: 5.6
• 作者: Stein,CherylR;Kaufman,JayS;Ford,CarolA;Leone,PeterA;Feldblum,PaulJ;Miller,WilliamC
• 通讯作者: Miller,WilliamC

A flexible Bayesian hierarchical model of preterm birth risk among US Hispanic subgroups in relation to maternal nativity and education.

美国西班牙裔亚群与产妇出生和教育相关的早产风险的灵活贝叶斯分层模型。

• DOI: 10.1186/1471-2288-11-51
• 发表时间: 2011
• 期刊: BMC medical research methodology
• 影响因子: 4
• 作者: Kaufman,JayS;MacLehose,RichardF;Torrone,ElizabethA;Savitz,DavidA
• 通讯作者: Savitz,DavidA