Course of Alcohol and Drug Problems in Treated Teens

接受治疗的青少年的酒精和毒品问题的过程

• 批准号: 7019200
• 负责人: Tammy Chung
• 金额: $ 34.44万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-06-01 至 2009-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7019200
• 关键词: Cannabis; adolescence (12-20); alcoholism /alcohol abuse therapy; behavioral /social science research tag; clinical research; drug /alcohol abstinence; drug abuse prevention; drug abuse therapy; health care model; human subject; longitudinal human study; model design /development; motivation; parent offspring interaction; patient oriented research; psychopathology; relapse /recurrence; smoking; substance abuse epidemiology

DESCRIPTION (provided by applicant): Research on the course of alcohol and substance problems in treated adolescents is limited largely to 1-year outcomes, Further, little is known about mechanisms of change underlying reductions in substance use because existing studies preclude fine-grained temporal analysis of substance use patterns, The proposed project will use intensive, time-limited short term follow-up over 1-year, combined with longer-term follow-up through 2-years to identify factors influencing course of substance use and problems, with an emphasis on alcohol, cannabis and tobacco. We will prospectively study a total of 300 adolescents (age 14-18), each with a parent collateral informant: 200 adolescents will be recruited from addictions treatment and 100 adolescents will be recruited from the community. The community sample will serve as a reference group to determine the clinical significance of changes observed in clinical participants. All adolescents will be assessed at baseline (within I week of treatment entry for clinical subjects). 6-, 12-, 18-, and 24-months. Clinical adolescents also will complete monthly phone follow-ups during the first year of follow-up. Monthly follow-along data during the first follow-up year and longer-term follow-up through 2-years will be used to address three specific aims: (1) to develop and validate a model of the course of substance use and problems that integrates shorter-term processes of response, remission, and relapse with longer-term processes of recovery and recurrence, (2) to characterize the time course and factors associated with the onset of different course processes for alcohol, cannabis and nicotine, (3) to identify pathways and predictors of the course of substance problems in treated youth. Results will provide important new information that will enhance the timing and content of substance use interventions for adolescents.

描述（由申请人提供）：对治疗青少年中酒精和物质问题的研究很大程度上仅限于1年的结果，此外，关于变化的降低机制的知识鲜物质使用和问题，重点是酒精，大麻和烟草。我们将前瞻性地研究总共300名青少年（14-18岁），每个人都有一个父母附带线人：将从成瘾治疗中招募200名青少年，并将从社区招募100名青少年。社区样本将作为参考组，以确定临床参与者观察到的变化的临床意义。 所有青少年将在基线时进行评估（临床受试者的治疗后一周内）。 6-，12-，18和24个月。临床青少年还将在随访的第一年完成每月的电话随访。在第一个随访年度和长期随访至2年期间，每月跟随数据将用于解决三个具体目标：（1）开发和验证供应，缓解，缓解，较短的响应过程以及与恢复和复发过程相关的长期过程的响应，缓解过程的问题的模型以及与gance canter的相关性，（2）与酒精相关的过程，（2）与酒精相关联，（2） （3）确定治疗青年物质问题进程的途径和预测指标。 结果将提供重要的新信息，以增强青少年物质使用干预措施的时间和内容。