Facilitating Aftercare for Alcohol Detox Patients

促进酒精戒毒患者的善后护理

• 批准号: 7066109
• 负责人: RICHARD D BLONDELL
• 金额: $ 25.05万
• 依托单位: STATE UNIVERSITY OF NEW YORK AT BUFFALO
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-05-15 至 2010-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7066109
• 关键词: alcoholism /alcohol abuse; alcoholism /alcohol abuse therapy; behavior therapy; behavioral /social science research tag; clinical research; clinical trials; drug /alcohol abstinence; drug detection; hospital patient care; human subject; human therapy evaluation; motivation; outcomes research; patient oriented research; peer group; posthospitalization care; psychological tests; questionnaires; self help organization; therapy design /development

DESCRIPTION (provided by applicant): There is little published information to guide evidence-based improvements in alcohol detoxification treatment that would lead to improved outcomes following hospitalization. As a result, inpatient detoxification clinical practices have changed little over the past 25 years. This application proposes a five-year period of support for the candidate, providing him with sufficient time and resources to develop as an independent researcher who will conduct trials of aftercare treatment initiation in alcohol detoxification settings. The candidate is an Addiction Medicine specialist who is currently an Associate Professor of Family Medicine at the University at Buffalo (UB). With an early background as a Family Medicine clinical educator at the University of Lousville (UofL), the candidate made a committed shift to a research career track in 1997 and completed a sabbatical in 1998. He then submitted an R01 proposal and a revision that were scored, but not funded. Following this, he resigned from a tenured, full-Professor position at UofL in 2003 and came to UB to seek sponsorship from UB's Research Institute on Addictions in preparation for this proposal. This career award will allow him to develop additional skills needed in treatment initiation theory and design, clinical trial methods, statistical analytic methods, and grantsmanship. A variety of formal and informal didactics during the early portion of the award period are planned to facilitate completion of career development objectives. However, the majority of the award period will be devoted to the supervised preparation for and completion of a pilot clinical trial, the submission of publications, and the submission of an R01 proposal. A novel Peer-delivered Twelve Step Facilitation (P-TSF) intervention will be developed for the pilot study based on the candidate's published preliminary work at UofL. The pilot clinical trial of this K23 will be conducted in the detoxification unit of a large hospital and will compare the treatment outcomes associated with two brief interventions ("Motivational Enhancement Therapy" or a P-TSF) and a "usual care" condition. The main outcome measures will be the initiation of aftercare (i.e. treatment/AA initiation) and percent days abstinent.

描述（由申请人提供）：几乎没有公开的信息来指导基于证据的酒精解毒治疗改善，这将导致住院后的结果改善。结果，在过去的25年中，住院排毒临床实践几乎没有改变。该申请提出了为候选人提供五年的支持，为他提供了足够的时间和资源来发展为独立研究人员，他们将在酒精排毒环境中进行及后护理治疗的试验。候选人是成瘾医学专家，目前是布法罗大学（UB）大学家庭医学副教授。候选人在卢斯维尔大学（UOFL）的家庭医学临床教育家（UOFL）的早期背景下，在1997年向研究职业赛道进行了承诺，并于1998年完成了休假。然后，他提交了R01提案和修订，并获得了评分，但没有资助。此后，他于2003年辞去了UOFL的终身制，完整的业务职位，并来到UB向UB的成瘾研究所寻求赞助，以准备这项提案。该职业奖将使他能够在治疗启动理论和设计，临床试验方法，统计分析方法和赠款技巧方面发展所需的其他技能。计划在奖励期的初期进行各种正式和非正式教学法，以促进完成职业发展目标。但是，该奖励期的大多数将专门用于监督的准备和完成试点临床试验，出版物提交以及提交R01提案的准备。基于候选人在UOFL上出版的初步工作，将开发一项新型的同行分配的十二步促进（P-TSF）干预措施。该K23的试点临床试验将在大型医院的排毒单元中进行，并将比较与两种短暂干预措施（“动机增强疗法”或P-TSF）和“常规护理”疾病相关的治疗结果。主要的结果指标将是启动后期护理（即治疗/AA启动）和节制的百分比。