The Pathology/Histology Core

病理学/组织学核心

• 批准号: 7140876
• 负责人: Yong-Jian Geng
• 金额: $ 8.56万
• 依托单位: UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-04-01 至 2011-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7140876
• 关键词: biomedical facility; confocal scanning microscopy; fluorescence microscopy; formaldehyde; histochemistry /cytochemistry; histopathology; immunocytochemistry; morphometry; tissue /cell preparation

Pathology Core, will provide histopathology services to all 6 projects in the Central Grant. The services will include routine preparation and histochemistry of paraffin and frozen aortic sections, regular immunostaining, and morphological analysis of the aortic tissue sections by bright field, fluorescence, and confocal microscopy. The Pathology Core also helps each project for morphometry analysis and histopathological sample preparation. In collaboration with other cores, patient's samples will be collected, fixed in formalin, banked, or otherwise stated in each project. Morophological and immunohistochemistry with antibodies against markers for vascular cells and inflammation as well as particular gene products identified by each project will be pursued. Each project will be supplied with a report and photodocumentation of relevant finding.

病理学核心将为中央拨款的所有 6 个项目提供组织病理学服务。这 服务将包括石蜡和冰冻主动脉切片的常规制备和组织化学、定期 通过明场、荧光和荧光技术对主动脉组织切片进行免疫染色和形态学分析 共焦显微镜。病理学核心还帮助每个项目进行形态测量分析和 组织病理学样品制备。与其他核心合作，将收集患者的样本， 在福尔马林中固定、储存或在每个项目中以其他方式说明。形态学和免疫组织化学 含有针对血管细胞和炎症标记物以及特定基因产物的抗体 将继续实施每个项目确定的目标。每个项目都将提供一份报告和 相关发现的照片文件。