The Pathology/Histology Core

病理学/组织学核心

• 批准号: 7140876
• 负责人: Yong-Jian Geng
• 金额: $ 8.56万
• 依托单位: UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-04-01 至 2011-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7140876
• 关键词: biomedical facility; confocal scanning microscopy; fluorescence microscopy; formaldehyde; histochemistry /cytochemistry; histopathology; immunocytochemistry; morphometry; tissue /cell preparation; biomedical facility; confocal scanning microscopy; fluorescence microscopy; formaldehyde; histochemistry /cytochemistry; histopathology; immunocytochemistry; morphometry; tissue /cell preparation

Pathology Core, will provide histopathology services to all 6 projects in the Central Grant. The services will include routine preparation and histochemistry of paraffin and frozen aortic sections, regular immunostaining, and morphological analysis of the aortic tissue sections by bright field, fluorescence, and confocal microscopy. The Pathology Core also helps each project for morphometry analysis and histopathological sample preparation. In collaboration with other cores, patient's samples will be collected, fixed in formalin, banked, or otherwise stated in each project. Morophological and immunohistochemistry with antibodies against markers for vascular cells and inflammation as well as particular gene products identified by each project will be pursued. Each project will be supplied with a report and photodocumentation of relevant finding.

病理核心将为中央赠款的所有6个项目提供组织病理学服务。这 服务将包括常规准备和石蜡和冷冻主动脉片的组织化学，常规 通过明亮场，荧光和 共聚焦显微镜。病理核心还有助于每个项目进行形态计算分析和 组织病理学样本制备。与其他核心合作，将收集患者的样本， 修复在福尔马林，在每个项目中均有其他说明。植物学和免疫组织化学 具有针对血管细胞和炎症标记的抗体以及特定基因产物 每个项目都确定。每个项目都将提供报告， 相关发现的光检查。