Microscopy Imaging Center for Research through Observation (MICRO)

显微镜成像观察研究中心 (MICRO)

• 批准号: 10488598
• 负责人: Petra Hoepcke Lenz
• 金额: $ 10.26万
• 依托单位: UNIVERSITY OF HAWAII AT MANOA
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-08-15 至 2023-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10488598
• 关键词: Aging; Applications Grants; Biological; Biological Sciences; Biomedical Research; Businesses; Centers of Research Excellence; Collaborations; Communities; Computer software; Computers and Advanced Instrumentation; Confocal Microscopy; Consultations; Core Facility; Custom; Data; Development; Educational workshop; Electron Microscope; Environment; Equipment; Eye; Fostering; Funding; Goals; Grant; Growth; Hawaii; Health; Human; Image; Image Analysis; Imaging technology; Infrastructure; Institution; Laboratories; Lasers; Microbe; Microdissection; Microscopy; Modernization; Names; Pathogenicity; Research; Research Activity; Research Infrastructure; Research Personnel; Research Project Grants; Research Support; Research Training; Role; Scanning; Schedule; Scientist; Services; Specialist; System; Technical Expertise; Techniques; Technology; Tissues; Training; Training Activity; Transmission Electron Microscopy; United States National Institutes of Health; Universities; Visit; biological research; career; design; fluorescence imaging; health goals; imaging facilities; improved; instrumentation; laser tweezer; microbiome; microbiome research; microorganism; microscopic imaging; outreach; programs; success; training opportunity; transmission process; webinar

Project Summary – CORE B: Microscopy Imaging Center for Research through Observation (MICRO) The Microscopy Imaging Center for Research through Observation (MICRO) Core of the Integrative Center for Environmental Microbiomes and Human Health (ICEMHH) will provide comprehensive imaging instrumentation and technical expertise at the University of Hawaiʻi at Mānoa (UHM) to support research that characterizes microorganisms and their relationship to each other, to host tissues or to their environment. The MICRO will incorporate and enhance the existing Biological Electron Microscope Facility that houses the only transmission electron microscope in the state, and the only scanning electron microscope at UHM supporting biological and biomedical research. The MICRO Core will provide the following: instrumentation, training and services for scanning and transmission electron microscopy, epifluorescent and confocal microscopy and laser microdissection and optical tweezers. A major goal of the COBRE support will be to modernize equipment and introduce users to new techniques, particularly rapidly changing fluorescent-imaging technologies, to assist in studies of microorganisms and their microbiomes. Relocation of the MICRO Core to a new Life Sciences Building, scheduled for completion in 2019, will provide a larger, custom-designed space for enhancing its research and training activities. The MICRO Core will be available to researchers across the UHM campus, to other local research and educational institutions, and to visiting scientists. The MICRO Core will favorably impact COBRE investigators and their affiliates by providing essential infrastructure and expertise to advance their research and foster collaborations that will positively impact the careers of junior investigators and more established investigators. The MICRO Core will support the growth of the ICEMHH, and (i) bring it visibility through its research and training efforts, (ii) staying abreast of advancing instrumentation and technologies in microscopy, and (iii) facilitation of outreach activities to characterize Hawaii's microbiomes.

项目摘要 – CORE B：观察研究显微成像中心 (MICRO) 显微镜成像观察研究中心 (MICRO) 综合中心的核心 环境微生物组和人类健康（ICEMHH）将提供全面的成像仪器 和夏威夷大学马诺阿分校 (UHM) 的技术专业知识，以支持具有以下特征的研究 微生物及其相互之间、与宿主组织或与其环境的关系。 合并并增强现有的生物电子显微镜设施，该设施拥有唯一的传输装置 该州的电子显微镜，也是 UHM 唯一支持生物和 MICRO Core 将提供以下服务：仪器、培训和服务。 扫描和透射电子显微镜、落射荧光和共焦显微镜以及激光 COBRE 支持的一个主要目标是实现设备和光镊的现代化。 向用户介绍新技术，特别是快速变化的荧光成像技术，以协助 微生物及其微生物组的研究将 MICRO Core 迁移到新的生命科学领域。 该建筑预计于 2019 年竣工，将提供更大的定制设计空间，以增强其功能 研究和培训活动将向整个 UHM 校园的研究人员开放。 其他当地研究和教育机构以及访问科学家将受到 MICRO Core 的青睐。 通过提供必要的基础设施和专业知识来推动 COBRE 调查人员及其附属机构的进步 他们的研究并促进合作，这将对初级研究人员等的职业产生积极影响 MICRO 核心将支持 ICEMHH 的发展，并且 (i) 提高其知名度。 通过其研究和培训工作，（ii）跟上先进仪器和技术的步伐 显微镜，以及 (iii) 促进外展活动，以表征夏威夷的微生物组。