CORE--ANALYTICAL LABORATORY

核心--分析实验室

• 批准号: 7110842
• 负责人: Adrian A Franke
• 金额: $ 8.83万
• 依托单位: UNIVERSITY OF HAWAII AT MANOA
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-07-01 至 2009-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7110842
• 关键词: analytical chemistry; biomedical equipment resource; biomedical facility; gas chromatography mass spectrometry; liquid chromatography mass spectrometry; neoplasm /cancer; analytical chemistry; biomedical equipment resource; biomedical facility; gas chromatography mass spectrometry; liquid chromatography mass spectrometry; neoplasm /cancer

This facility provides cost-effective and accurate chemical analyses for molecules relevant to research interests of Center investigators. It is also a base for consultation related to the quantisation of analytes and strategies in analytical chemistry. Services and expertise in advanced methods are available including state-of-the-art techniques, particularly liquid chromatography mass spectrometry (LC/MS) and gas chromatography mass spectrometry (GC/MS). In addition routine analyses and determinations of clinical markers are offered to investigators. No other laboratories are available to provide many of these services in the State of Hawaii. The high quality of services is continually monitored by taking part in internal and external quality assurance programs including the participation in round robin tests organized by the National Institute of Standards and Technology. The availability of this Shared Resource provides state-of-the-art services, improves feedback to the investigators, stimulates inter-disciplinary collaborations, and provides more cost-effective service to CRCH investigators. The current use at full capacity is anticipated to continue for the foreseeable future. Newly funded projects requiring services of the resource will outnumber projects terminating in the coming year. Equipment obtained through the CCSG support grant in the current cycle has greatly enhanced the potential of this resource. This facility has shown remarkable growth since its inception and its value to Center research is reflected in its broad usage, currently servicing eleven CRCH investigators from all three Programs, more than a twofold increase in service output the past four years, and the publication of 32 peer reviewed manuscripts in FY01-FY04 utilizing the shared resource.

该设施为与中心研究者的研究兴趣有关的分子提供了成本效益，准确的化学分析。它也是与分析化学中分析物和策略的量化有关的咨询基础。提供高级方法的服务和专业知识，包括最先进的技术，尤其是液相色谱质谱法（LC/MS）和气相色谱质谱法（GC/MS）。此外，还向研究人员提供了常规的分析和临床标记的确定。没有其他实验室可以在夏威夷提供许多此类服务。通过参加内部和外部质量保证计划，包括参与美国国家标准技术研究所组织的循环测试，不断监控高质量的服务。此共享资源的可用性提供了最先进的服务，改善了调查人员的反馈，刺激了跨学科的合作，并为CRCH调查人员提供了更具成本效益的服务。预计目前将在可预见的未来继续使用。需要资源服务的新资助的项目将超过来年终止的项目。通过当前周期中CCSG支持赠款获得的设备极大地增强了该资源的潜力。自从其成立和对中心研究的价值以来，该设施已经显着增长，反映在其广泛使用中，目前为所有三个计划的11个CRCH调查人员提供服务，在过去四年中，服务输出增加了两倍以上，以及使用共享资源的32名同行审查的01-FY04的同行审查的手稿。