Computational Tool for Simulation of Phonosurgery

用于模拟声音外科手术的计算工具

• 批准号: 6794845
• 负责人: Eric J Hunter
• 金额: $ 6.93万
• 依托单位: DENVER CENTER FOR THE PERFORMING ARTS
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-05-01 至 2007-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6794845
• 关键词: bioimaging /biomedical imaging; cartilage; computer simulation; image guided surgery /therapy; laryngoscopy; larynx; larynx muscle; ligaments; mathematical model; model design /development; muscle function; musculoskeletal imaging /visualization /scanning; phonology; physical model; prognosis; three dimensional imaging /topography; vocal cords; voice

DESCRIPTION (provided by applicant): The long-term goal of this project is to predict outcomes of laryngeal phonosurgery with physiologically based voice simulation. The proposed research will move towards this goal by developing a model of vocal fold posturing. Vocal fold posturing, a fundamental aspect of phonation control, is defined as adduction, abduction, or elongation of the vocal folds. Because posturing is based on laryngeal joint mechanics and soft tissue deformation, fundamental theories of continuum mechanics are used to formulate this model. The application of continuum mechanics to laryngeal posturing requires an accurate geometric and mechanical description of various tissues in the larynx, such as the vocal ligament and intrinsic laryngeal muscles. Furthermore, because many of these tissues are fibrous and thus have distinct lines of action, a portrayal of passive and contractile stress contributions and fiber direction is needed. The specific aims of the current project are: I. To mathematically represent the orientation of differentiated laryngeal muscle bundles, allowing for distributed muscle forces over various cartilages. II. To create, with the distribution of intrinsic muscle bundles, a three-dimensional finite element model of vocal fold mechanics that can predict both the speed and the range of vocal fold medialization and lateralization. III. To simulate a Type I thyroplasty phonosurgery and predict the resultant glottal configuration as well as the resultant stress distribution in the repaired vocal fold. It is expected that the posturing model will have a significant impact on surgically based voice therapies, as well as on vocal fold modeling in general and post-surgical therapy.

描述（由申请人提供）：该项目的长期目标是通过基于生理学的语音模拟来预测喉音手术的结果。拟议的研究将通过开发声带姿势模型来实现这一目标。声带姿势是发声控制的一个基本方面，被定义为声带的内收、外展或伸长。由于姿势是基于喉关节力学和软组织变形，因此使用连续介质力学的基本理论来制定该模型。连续介质力学在喉部姿势中的应用需要对喉部各种组织（例如声带韧带和喉内肌）进行精确的几何和力学描述。此外，由于许多这些组织是纤维状的，因此具有不同的作用线，因此需要描述被动和收缩应力的贡献以及纤维方向。当前项目的具体目标是： I. 以数学方式表示分化的喉肌束的方向，允许在各种软骨上分布肌肉力量。 二.根据内在肌束的分布，创建声带力学的三维有限元模型，该模型可以预测声带内侧化和外侧化的速度和范围。 三．模拟 I 型甲状软骨成形术语音外科手术并预测最终的声门结构以及修复后声带中的最终应力分布。 预计姿势模型将对基于手术的发声治疗以及一般和术后治疗中的声带建模产生重大影响。