COMPUTATIONAL BIOLOGY & BIOINFORMATICS

计算生物学

• 批准号: 7336051
• 负责人: Tsegaye Habtemariam
• 金额: $ 2.14万
• 依托单位: TUSKEGEE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-06-01 至 2007-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7336051
• 关键词: COMPUTATIONAL; BIOLOGY; BIOINFORMATICS

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This project focuses upon Infrastructure development in Computational Biology and Bioinformatics as part of the Core Resources at the Center for Biomedical Research (CBR) at Tuskegee University. Research involving advanced information technologies, the Internet and databases is crucial in examining and analyzing patterns of disease occurrence, genetic traits and molecular level dynamics. The key strategy in our endeavors in the core Bioinformatics is to upgrade the infrastructure and expertise of our scientists in computational biology and bioinformatics, acquire advanced computational and network resources and promote active research that exploits these technologies in health disparity studies. Server Development: We have migrated to a Linux server (Red Hat Enterprise Linux ES). We have moved all our data into the new server. We have also put some of the software on the server to be accessible to computers on the TU campus. Website development: A new website development has been completed and will be tested and soon be online. We have also started the base line links and data to be used for scientists interested in the area of Bioinformatics and Health disparities. Research Coordination Network (RCN): Discussed collaboration with Montgomery Aids Outreach (MAO) over some period of time and have now agreed upon a partnership with MAO with detailed protocol to collect data from the black belt counties (BBC) of Alabama. Sponsoring the sixth annual biomedical research symposium: As part of the strategy to promote sharing of biomedical research activities that are in progress as well as to address national issues dealing with Health Disparities, CCEBRA has organized the sixth annual biomedical research symposium that was held September 29-30, 2005 at the Kellogg Conference Center, Tuskegee University. Shared Resource: CCEBRA has been providing service in statistical analysis for faculties and researchers in TU. Developed sharable data sources related to the health disparities project that included HIV/AIDS, infant mortality rate, cancer, diabetes and cardiovascular diseases for the BBC in Alabama as well as other comparison counties. Created summary tables, graphs and maps using GIS tools. Made the databases available (hardcopy and electronic formats) to be shared by scientists who need information to advance biomedical research dealing with health disparities studies in Alabama with a special focus on the Black Belt and rural counties of Alabama. NCBI filed guide in Tuskegee University: The National Center for Biotechnology Information (NCBI), a division of the National Library of Medicine has led the way in establishing useful bioinformatics resources for the biomedical research community, including PubMed, GenBank, Entrez and others. In the week of August 27, 2006, our center at Tuskegee University will host a course entitled "A Field Guide to GenBank and NCBI Molecular Biology Resources". The course will be given by instructors from NCBI. Timely reminders will also be posted. The seminar is intended for Tuskegee University RCMI scientists and faculty, staff and students from other areas of the Tuskegee University campus. Certificates of Attendance from NCBI will also be given to workshop participants.

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子弹和调查员（PI）可能已经从其他NIH来源获得了主要资金，因此可以在其他清晰的条目中代表。列出的机构适用于该中心，这不一定是调查员的机构。该项目的重点是计算生物学和生物信息学的基础设施发展，这是塔斯基吉大学生物医学研究中心（CBR）的核心资源的一部分。涉及高级信息技术，互联网和数据库的研究对于检查和分析疾病发生，遗传特征和分子水平动态的模式至关重要。核心生物信息学努力的关键策略是升级我们在计算生物学和生物信息学方面的科学家的基础架构和专业知识，获取先进的计算和网络资源，并促进积极的研究，以利用这些技术在健康不足研究中。服务器开发：我们已迁移到Linux服务器（Red Hat Enterprise Linux ES）。我们已经将所有数据移至新服务器中。我们还将服务器上的一些软件放在TU校园的计算机上可以访问。网站开发：一项新的网站开发已经完成，将进行测试，并将很快在线。我们还启动了基本链接和数据，用于对生物信息学和健康差异领域感兴趣的科学家。研究协调网络（RCN）：在一段时间内与蒙哥马利艾滋病外展（MAO）进行了讨论，现在已经同意与毛泽东建立合作伙伴关系，并通过详细的协议收集来自阿拉巴马州黑带县（BBC）的数据。赞助第六届年度生物医学研究研讨会：作为促进正在进行的生物医学研究活动以及解决与健康差异有关的国家问题的战略的一部分，Ccebra组织了第六届年度生物医学研究研讨会，该研讨会于9月29日举行-30，2005在塔斯基吉大学的凯洛格会议中心。共享资源：Ccebra一直在为TU的教师和研究人员提供统计分析中的服务。开发了与健康差异项目相关的可共享数据来源，该项目包括艾滋病毒/艾滋病，婴儿死亡率，癌症，糖尿病和心血管疾病以及阿拉巴马州的其他比较县。使用GIS工具创建了摘要表，图形和地图。使数据库可用（硬拷贝和电子格式）由科学家共享，他们需要信息来推进阿拉巴马州健康差异研究的生物医学研究，特别关注阿拉巴马州黑带和农村县。 NCBI提交了塔斯基吉大学的指南：国家生物技术信息中心（NCBI），国家医学图书馆的一个部门，促进了为生物医学研究社区建立有用的生物信息学资源，包括PubMed，Gen​​bank，Entrez等。在2006年8月27日，我们在塔斯基吉大学的中心将举办一门题为“ GenBank和NCBI分子生物学资源的实地指南”课程。该课程将由NCBI的讲师提供。及时提醒也将发布。该研讨会旨在为Tuskegee University RCMI科学家和教职员工，来自Tuskegee University校园其他领域的教职员工和学生。 NCBI的出勤证明也将授予研讨会参与者。