A Lifestyle Change Program to Prevent Type 2 Diabetes

预防 2 型糖尿病的生活方式改变计划

基本信息

批准号：
7122058
负责人：
ROBIN G WHITTEMORE
金额：
$ 23.95万
依托单位：
YALE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2005
资助国家：
美国
起止时间：
2005-09-15 至 2008-08-31
项目状态：
已结题

项目摘要

DESCRIPTION (provided by applicant): This application seeks support for a pilot study to reduce the risk of type 2 diabetes in at-risk adults with a lifestyle change program provided by nurse practitioners (NPs) in primary care settings. Type 2 diabetes is one of the most rapidly increasing chronic illnesses worldwide and is associated with significant morbidity, mortality, personal suffering, and societal costs. The imperative for primary prevention of type 2 diabetes has increasingly been emphasized by health care organizations, governmental agencies, and policy initiatives. Several large clinical trials have convincingly established that lifestyle change programs can significantly prevent or delay the onset of type 2 diabetes in at-risk adults. Yet, questions remain regarding how to successfully implement these programs to the population at-large as the tested programs were intensive in terms of time and resources. Research is urgently needed to determine best practices to promote lifestyle change and prevent type 2 diabetes. Thus, this multi-phase pilot study has the following aims: 1. To modify a research-based lifestyle change program based on the Diabetes Prevention program collaboratively with NPs for implementation in primary care settings. 2. To evaluate the preliminary effects of the modified lifestyle change program provided by NPs to adults at-risk for type 2 diabetes on clinical outcomes [glucose tolerance test (GTT), insulin resistance (IR), body mass index (BMI), blood pressure (BP), lipid profile], behavioral outcomes (health promoting behaviors, diet and exercise behaviors), quality of life (QOL), and weight loss self- efficacy. 3. To explore the reach, adoption, implementation, and maintenance of a lifestyle change program delivered by NPs in primary care settings.

描述（由申请人提供）：本申请寻求对一项试点研究的支持，以通过初级保健机构的执业护士 (NP) 提供的生活方式改变计划来降低高危成人患 2 型糖尿病的风险。 2 型糖尿病是全世界增长最快的慢性疾病之一，与显着的发病率、死亡率、个人痛苦和社会成本相关。医疗保健组织、政府机构和政策倡议日益强调 2 型糖尿病一级预防的必要性。几项大型临床试验令人信服地证实，生活方式改变计划可以显着预防或延缓高危成人 2 型糖尿病的发病。然而，由于测试的项目需要大量时间和资源，因此如何向广大民众成功实施这些项目仍然存在问题。迫切需要进行研究以确定促进生活方式改变和预防 2 型糖尿病的最佳实践。因此，这项多阶段试点研究的目标如下： 1. 与 NP 合作，根据糖尿病预防计划修改基于研究的生活方式改变计划，以便在初级保健机构中实施。 2. 评估 NP 向有 2 型糖尿病风险的成年人提供的生活方式改变计划对临床结果的初步影响 [葡萄糖耐量试验 (GTT)、胰岛素抵抗 (IR)、体重指数 (BMI)、血液压力（BP）、血脂状况]、行为结果（健康促进行为、饮食和运动行为）、生活质量（QOL）和减肥自我效能。 3. 探索初级保健机构中 NP 提供的生活方式改变计划的影响范围、采用、实施和维持。