A Lifestyle Change Program to Prevent Type 2 Diabetes

预防 2 型糖尿病的生活方式改变计划

• 批准号: 7033782
• 负责人: ROBIN G WHITTEMORE
• 金额: $ 24.53万
• 依托单位: YALE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-09-15 至 2007-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7033782
• 关键词: behavioral /social science research tag; blood lipid; blood pressure; body composition; clinical research; clinical trials; diabetes education; diabetes risk; dietary control; disease /disorder prevention /control; education evaluation /planning; exercise; glucose tolerance test; group counseling; health care service evaluation; health services research tag; human subject; human therapy evaluation; insulin sensitivity /resistance; interview; lifestyle; noninsulin dependent diabetes mellitus; nurse practitioners; obesity; prediabetic state; primary care physician; quality of life

DESCRIPTION (provided by applicant): This application seeks support for a pilot study to reduce the risk of type 2 diabetes in at-risk adults with a lifestyle change program provided by nurse practitioners (NPs) in primary care settings. Type 2 diabetes is one of the most rapidly increasing chronic illnesses worldwide and is associated with significant morbidity, mortality, personal suffering, and societal costs. The imperative for primary prevention of type 2 diabetes has increasingly been emphasized by health care organizations, governmental agencies, and policy initiatives. Several large clinical trials have convincingly established that lifestyle change programs can significantly prevent or delay the onset of type 2 diabetes in at-risk adults. Yet, questions remain regarding how to successfully implement these programs to the population at-large as the tested programs were intensive in terms of time and resources. Research is urgently needed to determine best practices to promote lifestyle change and prevent type 2 diabetes. Thus, this multi-phase pilot study has the following aims: 1. To modify a research-based lifestyle change program based on the Diabetes Prevention program collaboratively with NPs for implementation in primary care settings. 2. To evaluate the preliminary effects of the modified lifestyle change program provided by NPs to adults at-risk for type 2 diabetes on clinical outcomes [glucose tolerance test (GTT), insulin resistance (IR), body mass index (BMI), blood pressure (BP), lipid profile], behavioral outcomes (health promoting behaviors, diet and exercise behaviors), quality of life (QOL), and weight loss self- efficacy. 3. To explore the reach, adoption, implementation, and maintenance of a lifestyle change program delivered by NPs in primary care settings.

描述（由申请人提供）： 该申请寻求支持试点研究，以降低高危成年人中2型糖尿病的风险，其中包括护士从业人员（NPS）在初级保健环境中提供的生活方式改变计划。 2型糖尿病是全球慢速增长的慢性疾病之一，与大量发病率，死亡率，个人痛苦和社会成本有关。卫生保健组织，政府机构和政策计划越来越强调了主要预防2型糖尿病的必要性。 几项大型临床试验令人信服地确定，生活方式改变计划可以显着防止或延迟处于危险的成年人中2型糖尿病的发作。然而，由于测试计划在时间和资源方面非常密集，因此如何成功地将这些计划成功地针对人口实施。迫切需要进行研究以确定促进生活方式改变并防止2型糖尿病的最佳实践。因此，这项多相试验研究具有以下目的： 1。修改基于研究的生活方式改变计划，基于预防糖尿病计划，与NPS合作，以在初级保健环境中实施。 2。评估NPS提供的修改后的生活方式改变计划的初步影响2型糖尿病的成年人对临床结果[葡萄糖耐受性测试（GTT），胰岛素抵抗（IR），体重指数（BMI），血压（BP），血压（BP），Lipid Profiles，Lipid Praction，行为促进行为和Quardion Quardies Quardion和Quancie行为（Quance）的行为和Quardion Quardion Quancie Quancie（葡萄糖耐受性测试（GTT），胰岛素耐药性（IR），Quanc.和减肥自功效。 3。探索NP在初级保健环境中提供的生活方式改变计划的覆盖范围，采用，实施和维护。