Center on Molecular and Cell Biology of Drug Abuse

药物滥用分子和细胞生物学中心

• 批准号: 6788693
• 负责人: HORACE LOH
• 金额: $ 101.65万
• 依托单位: UNIVERSITY OF MINNESOTA
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-09-30 至 2008-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6788693
• 关键词: cell biology; drug abuse; molecular biology; opioid receptor; pharmacology

DESCRIPTION (provided by applicant): Basic Research Center on Molecular and Cell Biology of Drug Abuse (BRCMCDA) was established in 1998 with the objectives to (1) to foster interdisciplinary approaches in drug addiction research; (2) to serve as an "activity" center to coordinate and to promote all academic and scholarly activities on drug addiction research at University of Minnesota; (3) to serve as a national resource for molecular and cell biology of drug addiction research: and (4) to serve as training center for young scientists here at University of Minnesota. The goal of the Center is to promote molecular and cell biology approaches for drug addiction research, hence a thematic program is absent in the 8 scientific components. Instead, multidisciplinary approaches in the programs present fertile ground for training and interaction among scientists. The Center's activities include sponsored seminars and biannual symposium focus on the state-of-the-art techniques and breakthroughs in the field of drug addiction research. The Center has continued to raise the visibility of drug addiction research at University of Minnesota and has served as national resources in supplying investigators nationally and internationally reagents and genetically altered mice for their research programs. We wish to build on the past success and continue the missions of BRCMCBDA in promoting drug addiction research and training at University of Minnesota. Thus the proposed structure of BRCMCBDA remains to consist of 8 scientific components supported by an administrative core. The principal investigators involved in these components have demonstrated records of past collaboration and are committed to the mission of the Center. However, in order to establish a formal recruiting mechanism, a "seed grants" program will be implemented to create an opportunity for investigators not associated with the Center to test their hypotheses or new techniques in drug addiction research. Such program not only will enhance the existing research programs within the Center, but also will establish the bases for future components of the Center and grants application in drug addiction research. Hence, together with the other programs of the Center, BRCMCBDA will continue to be a research training center and national resource on the understanding of the molecular mechanism of drug addiction.

描述（由申请人提供）： 药物滥用分子和细胞生物学基础研究中心 (BRCMCDA) 成立于 1998 年，其目标是 (1) 促进药物成瘾研究的跨学科方法； (2) 作为“活动”中心，协调和促进明尼苏达大学有关毒瘾研究的所有学术和学术活动； (3) 充当药物成瘾研究分子和细胞生物学的国家资源：(4) 充当明尼苏达大学年轻科学家的培训中心。该中心的目标是促进药物成瘾研究的分子和细胞生物学方法，因此 8 个科学组成部分中没有主题计划。相反，这些项目中的多学科方法为科学家之间的培训和互动提供了肥沃的土壤。该中心的活动包括赞助研讨会和每两年一次的研讨会，重点关注毒瘾研究领域的最先进技术和突破。该中心继续提高明尼苏达大学吸毒成瘾研究的知名度，并作为国家资源为国内外研究人员提供研究项目所需的试剂和转基因小鼠。我们希望在过去的成功基础上继续 BRCMCBDA 的使命，促进明尼苏达大学的毒瘾研究和培训。因此，BRCMCBDA 的拟议结构仍然由 8 个科学组成部分组成，并由一个行政核心支持。参与这些组成部分的主要研究人员已经证明了过去的合作记录，并致力于中心的使命。不过，为了建立正式的招募机制，将实施“种子资助”计划，为与中心无关的研究人员创造机会，测试他们在毒瘾研究中的假设或新技术。该项目不仅将加强中心现有的研究项目，还将为中心未来的组成部分和毒瘾研究的资助申请奠定基础。因此，与该中心的其他项目一起，BRCMCBDA 将继续成为了解毒瘾分子机制的研究培训中心和国家资源。