Sleep and Obesity in Adolescents

青少年的睡眠和肥胖

• 批准号: 7112097
• 负责人: ANDREA MARY LANDIS
• 金额: $ 2.82万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-06-01 至 2009-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7112097
• 关键词: actigraphy; adolescence (12-20); appetite; behavioral /social science research tag; body composition; clinical research; disease /disorder proneness /risk; health behavior; human subject; hunger; obesity; personal log /diary; predoctoral investigator; satiations; sleep; sleep disorders; wakefulness

DESCRIPTION (provided by applicant): One modifiable risk factor for obesity that has received considerably little, if any, attention is sleep. However, recent studies in children and adults have shown that total amount of sleep is inversely associated with body mass index (BMI), an observation not well characterized in adolescents. Sleep/wake disruption has the potential to impact selected endocrine systems and metabolic paths that can cause changes in hunger and satiety, promoting excess eating and leading to obesity. Because of the high prevalence of both obesity and compromised sleep in this group, the purpose of this study is to explore associations among sleep/wake disruption, hunger, satiety, and BMI in a group normal of weight, at risk for overweight, and overweight adolescents 14-18 years old. Subjects will complete the Pittsburgh Sleep Quality Index, Pediatric Daytime Sleepiness Scale, wear a wrist actigraph, and record a sleep, hunger, and satiety diary for eight days. The results of the work will provide valuable data on sleep and hunger. This study has the potential to enhance clinical practice through the translation of basic science concepts into the development and testing of innovative interventions that may subsequently help to improve sleep and decrease adolescent obesity.

描述（由申请人提供）：肥胖的一种可修改风险因素，其注意力很少（如果有的话）是睡眠。但是，最近对儿童和成人的研究表明，总的睡眠量与体重指数（BMI）成反比，这是青少年未充分表征的观察结果。睡眠/尾流中断有可能影响选定的内分泌系统和代谢路径，这可能会导致饥饿和饱腹的变化，促进饮食过多并导致肥胖。由于这组肥胖症和睡眠的高度流行，这项研究的目的是探索一个正常的体重，有超重和超重的青少年14-18岁的年龄较大的体重，探索睡眠/唤醒，饥饿，饱腹感和BMI之间的关联。受试者将完成匹兹堡的睡眠质量指数，小儿白天嗜睡量表，戴上手腕画，并记录八天的睡眠，饥饿和饱腹度日记。工作的结果将提供有关睡眠和饥饿的宝贵数据。这项研究有可能通过将基础科学概念转化为创新干预措施的开发和测试，从而增强临床实践，这些干预措施随后可能有助于改善睡眠并减少青少年肥胖。