Buprenorphine for Opioid Dependence in Primary Care

丁丙诺啡在初级保健中治疗阿片类药物依赖

基本信息

  • 批准号:
    7113205
  • 负责人:
  • 金额:
    $ 17.67万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2005
  • 资助国家:
    美国
  • 起止时间:
    2005-08-20 至 2010-06-30
  • 项目状态:
    已结题

项目摘要

DESCRIPTION (provided by applicant): Office-based buprenorphine treatment promises to expand treatment access for opioid dependent individuals. Yet physicians have been reluctant to begin prescribing the medication, indicating a compelling need to develop innovative strategies to train physicians and integrate buprenorphine treatment into medical practice. The goal of this mentored clinical scientist award is to enhance the developing clinical research skills of Erik Gunderson, M.D. through research on integrating buprenorphine treatment of opioid dependence in primary care. After completing a substance abuse fellowship, Dr. Gunderson joined the faculty in the Division as an Assistant Clinical Professor of Medicine in Psychiatry, working both in a primary care clinic and at a specialty buprenorphine treatment program. His pilot data on integrated opioid dependence treatment provide preliminary support for the feasibility and effectiveness of buprenorphine in primary care. Dr. Gunderson has received funding through a pilot study program of the Division's NIDA-funded center grant and an private foundation to study medical education on substance abuse. However, to become an independent clinical researcher, he will need formal course work, mentoring, and release of time from his extensive clinical and administrative responsibilities. During the next several years, Dr. Gunderson plans to conduct mentored formative research and a clinical trial on integrated buprenorphine treatment in primary care versus a specialty clinic setting. This research and additional training will prepare him to meet his long term research career goal of improving and expanding treatment of substance abuse in primary care. Under the sponsorship and guidance of Dr. Frances Levin, together with other faculty, Dr. Gunderson's training plan combines formal course work with clinical research experience. He will work closely with preceptors to receive training in the following areas: methods of integrating opioid dependence treatment into primary care, clinical treatment trial study design and interpretation, and biostatisties. Specifically, his research plan includes a demonstration project to determine the feasibility and effectiveness of buprenorphine maintenance delivered by general internists in a primary care clinic. Findings from this project will be used to inform development of a randomized trial of the effectiveness of buprenorphine maintenance delivered in primary care versus a specialty clinic. The combined mentoring, training and research plan will provide Dr. Gunderson with unique training enabling him to develop an independent research career focused on integrating substance abuse treatment in primary care.
描述(由申请人提供): 基于办公室的丁丙诺啡治疗有望扩大阿片类药物依赖人的治疗机会。然而,医师一直不愿开始开处方药物,这表明需要制定创新的策略来培训医生并将丁丙诺啡治疗整合到医疗实践中。这项指导的临床科学家奖的目的是通过将阿片类药物依赖性在初级保健中整合丁丙诺啡治疗的研究来提高埃里克·甘德森(Erik Gunderson)的发展临床研究技能。完成一项滥用药物奖学金后,Gunderson博士加入该部门的教职员工,担任精神病学医学助理临床教授,在初级保健诊所和专业丁丙诺啡治疗计划中工作。他关于综合阿片类药物依赖治疗的试验数据为丁丙诺啡在初级保健中的可行性和有效性提供了初步支持。 Gunderson博士通过该部门的NIDA资助中心赠款和研究滥用药物的医学教育的试点研究计划获得了资金。但是,要成为一名独立的临床研究人员,他将需要正式的课程工作,指导和从他的广泛临床和行政责任中释放时间。在接下来的几年中,Gunderson博士计划在初级保健与专业诊所环境中对丁丙诺啡综合治疗进行指导的形成性研究和临床试验。这项研究和额外的培训将使他为他的长期研究职业目标做好准备,以改善和扩大初级保健药物滥用的治疗方法。在弗朗西斯·莱文(Frances Levin)博士的赞助和指导下,甘德森博士的培训计划将正式课程工作与临床研究经验相结合。他将与受体紧密合作,以在以下领域接受培训:将阿片类药物依赖治疗融入初级保健,临床治疗试验研究设计和解释以及生物统计学的方法。具体而言,他的研究计划包括一个示范项目,以确定普通内科医生在初级保健诊所提供的丁丙诺啡维持的可行性和有效性。该项目的发现将用于为开发一项随机试验的开发,该试验涉及在初级保健中提供的丁丙诺啡维持的有效性与专业诊所的有效性。合并的指导,培训和研究计划将为Gunderson博士提供独特的培训,使他能够开发独立的研究职业,重点是将药物滥用治疗纳入初级保健。

项目成果

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ERIK W GUNDERSON其他文献

ERIK W GUNDERSON的其他文献

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{{ truncateString('ERIK W GUNDERSON', 18)}}的其他基金

Buprenorphine for Opioid Dependence in Primary Care
丁丙诺啡在初级保健中治疗阿片类药物依赖
  • 批准号:
    7643405
  • 财政年份:
    2005
  • 资助金额:
    $ 17.67万
  • 项目类别:
Buprenorphine for Opioid Dependence in Primary Care
丁丙诺啡在初级保健中治疗阿片类药物依赖
  • 批准号:
    6959689
  • 财政年份:
    2005
  • 资助金额:
    $ 17.67万
  • 项目类别:
Buprenorphine for Opioid Dependence in Primary Care
丁丙诺啡在初级保健中治疗阿片类药物依赖
  • 批准号:
    7798293
  • 财政年份:
    2005
  • 资助金额:
    $ 17.67万
  • 项目类别:
Buprenorphine for Opioid Dependence in Primary Care
丁丙诺啡在初级保健中治疗阿片类药物依赖
  • 批准号:
    7462366
  • 财政年份:
    2005
  • 资助金额:
    $ 17.67万
  • 项目类别:

相似国自然基金

曲马多与阿片类药物的多药滥用及其机制的研究
  • 批准号:
    30870894
  • 批准年份:
    2008
  • 资助金额:
    28.0 万元
  • 项目类别:
    面上项目

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Adoption of Buprenorphine in an HMO Setting
在 HMO 环境中采用丁丙诺啡
  • 批准号:
    6866860
  • 财政年份:
    2005
  • 资助金额:
    $ 17.67万
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阿片类药物治疗对功能的影响
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阿片类药物依赖妇女的胎儿和婴儿神经行为
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    7107294
  • 财政年份:
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  • 资助金额:
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Predictors of Relapse to Prescription Opioid Abuse Among Pain Patients
疼痛患者处方阿片类药物滥用复发的预测因素
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  • 财政年份:
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  • 资助金额:
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Counseling for Primary Care Office-Based Buprenorphine
初级保健办公室丁丙诺啡咨询
  • 批准号:
    7113846
  • 财政年份:
    2005
  • 资助金额:
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