Emotion, communication, & EEG: Development & risk

情感、沟通、

• 批准号: 7144489
• 负责人: DANIEL S MESSINGER
• 金额: $ 30.57万
• 依托单位: UNIVERSITY OF MIAMI CORAL GABLES
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-08-01 至 2011-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7144489
• 关键词: attention; autism; behavior prediction; behavior test; behavioral /social science research tag; child psychology; clinical research; cognition; communication behavior; diagnosis design /evaluation; disease /disorder proneness /risk; early experience; electroencephalography; emotions; face expression; infant human (0-1 year); interpersonal relations; mental disorder diagnosis; neuropsychology; paralinguistic behavior; parent offspring interaction; personality; preschool child (1-5); psychopathology; siblings; social behavior

DESCRIPTION (provided by applicant): This project will use developmental patterns of early emotional functioning and communication to predict social, behavioral, and cognitive functioning in the second and third year of life. Contrasts between 100 typically developing infant siblings and 100 infant siblings of children with Autism Spectrum Disorder (ASD) - who are at risk for a range of disruptions of emotion, communication, and cognition - will illuminate these developmental processes from a developmental psychopathology perspective. In the first year of life, associations between temperamental (Lab-TAB) and communicative (face-to-face/still-face) assessments of positive and negative emotion, cerebral indices of approach motivation (EEG laterality), and the development of communicative intentionality (infant joint attention) will be determined. These constructs will be used to predict a set of developmental^ linked processes including dyadic relationship quality, parent rated behavioral difficulties and strengths, standardized measures of linguistic and cognitive functioning, and ASD- related symptomatology in the second and third year of life. Relationship quality is a central construct, encompassing security of attachment, parental warmth and control, and child cooperation and warmeth in a range of social situations. Relationship quality is expected to mediate pathways to all outcomes with the exception of ASD symptomatology. Children with high levels of ASD symptomatology are expected to show deficits in both early measures emotional communication and later measures of social, communicative, and cognitive functioning. ASD symptomatology is expected to be directly related to early emotional functioning. This proposal utilizes multi-method assessment of emotional functioning early in infancy to confront the task of predicting intentional communication and later indices of healthy interaction, and competent linguistic and cognitive functioning. The models tested will shed specific light on the prediction and prevention of health- related outcomes including behavior problems, poor relationship quality, and ASD symptomatology in an at- risk and typically developing sample. Examination of predictive associations in typically developing infants and infant siblings of children with ASD will shed light on pathways to healthy development, psychopathologic deviations from those pathways, and potential intervention strategies for infants at risk for developmental difficulties.

描述（由申请人提供）：该项目将利用早期情绪功能和沟通的发展模式来预测第二年和第三年的社交、行为和认知功能。对 100 个正常发育的婴儿兄弟姐妹和 100 个患有自闭症谱系障碍 (ASD) 儿童的婴儿兄弟姐妹（他们面临一系列情绪、沟通和认知障碍的风险）进行对比，将从发展精神病理学的角度阐明这些发展过程。在生命的第一年，积极和消极情绪的气质（Lab-TAB）和交流（面对面/静止）评估之间的关联，接近动机的大脑指数（脑电图偏侧性）以及交流能力的发展意向性（婴儿共同注意力）将被确定。这些构建将用于预测一组与发展相关的过程，包括二元关系质量、父母评定的行为困难和优势、语言和认知功能的标准化测量以及生命第二年和第三年的 ASD 相关症状。关系质量是一个核心概念，包括依恋的安全感、父母的温暖和控制、以及孩子在各种社交场合的合作和温暖。关系质量预计会介导除 ASD 症状外的所有结果。患有高水平自闭症谱系障碍症状的儿童预计会在早期情绪沟通测量和后期社交、沟通和认知功能测量中表现出缺陷。 ASD 症状预计与早期情绪功能直接相关。该提案利用婴儿早期情绪功能的多种方法评估来应对预测有意沟通和后期健康互动指标以及能力语言和认知功能的任务。测试的模型将具体阐明健康相关结果的预测和预防，包括高危和典型发展样本中的行为问题、不良关系质量和自闭症谱系障碍症状。对典型发育婴儿和自闭症谱系障碍儿童的婴儿兄弟姐妹的预测关联的检查将揭示健康发育的途径、这些途径的心理病理偏差以及对有发育困难风险的婴儿的潜在干预策略。