Alcohol Health Disparities in 2 Indian Populations

两个印度人群的酒精健康差异

• 批准号: 6784523
• 负责人: DOUGLAS K NOVINS
• 金额: $ 37.2万
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-09-01 至 2006-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6784523
• 关键词: American; Native Americans; United States; adolescence (12-20); alcoholism /alcohol abuse; clinical research; comorbidity; epidemiology; health; human data; human middle age (35-64); human population study; mental disorders; mental health epidemiology; racial /ethnic difference; substance abuse epidemiology; substance abuse related disorder; young adult human (21-34)

DESCRIPTION (provided by applicant): The use and abuse of alcohol among American Indians (AI) is a major public health concern. To date, the best information derives from adolescent populations. Compared to their non-AI counterparts, AI youth are more likely to use alcohol, more likely to become problem drinkers, more likely to meet diagnostic criteria for alcohol abuse and dependence, more likely to use alcohol in combination with drugs, and more likely to have both an alcohol use disorder and a psychiatric disorder. From service system data and vital statistics, we know that AIs generally are more likely to develop a variety of physical health conditions that are related to alcohol use and to die from alcohol-related causes. Research to date also suggests that rates of the alcohol-related health disparities (ARHDs) vary substantially across AI tribes. Despite the compelling nature of these disparities, surprisingly little is known regarding key aspects of their descriptive and analytical epidemiology. Indeed, the specific relationships of alcohol use, abuse, and dependence with co morbid drug, psychiatric, and physical health conditions among AI adults are largely unexplored. Yet findings from studies focused on the US general population suggest that these interrelationships are critical for understanding ARHDs. The goal of this project is to analyze data from the recently completed American Indian Service Utilization, Psychiatric Epidemiology, and Risk/Protective Factors Project - the first large-scale, population-based study of AIs between the ages of 15 and 54. The specific aims for this project are as follows: 1) to describe disparities in the epidemiology of alcohol use across 2 AI population-based samples of 15-54 year-olds as well as between these 2 AI samples and samples representative of the US general population; 2) to conduct a parallel investigation regarding disparities in the epidemiology of alcohol abuse and dependence in these same samples; 3) to extend this line of inquiry to explore disparities in the epidemiology of drug use, abuse, and dependence co morbid with alcohol use, abuse and dependence; 4) to depict disparities in the epidemiology of non-substance use psychiatric disorders co morbid with alcohol use, abuse, and dependence; and 5) to investigate disparities in the epidemiology of physical health conditions co morbid with alcohol use, abuse, and dependence across these 2 AI tribes and between these tribes and the US general population.

描述（由申请人提供）：美洲印第安人 (AI) 的饮酒和滥用是一个主要的公共卫生问题。迄今为止，最好的信息来自青少年群体。与非人工智能同行相比，人工智能青年更有可能饮酒，更有可能成为酗酒者，更有可能符合酒精滥用和酒精依赖的诊断标准，更有可能将酒精与药物结合使用，并且更有可能同时患有酒精使用障碍和精神疾病。从服务系统数据和生命统计数据中，我们知道人工智能通常更有可能出现与饮酒相关的各种身体健康状况，并死于与酒精相关的原因。迄今为止的研究还表明，人工智能部落中与酒精相关的健康差异（ARHD）的比率差异很大。尽管这些差异具有引人注目的性质，但令人惊讶的是，人们对其描述性和分析性流行病学的关键方面知之甚少。事实上，人工智能成年人中饮酒、滥用和依赖与共病药物、精神和身体健康状况的具体关系在很大程度上尚未被探索。然而，针对美国普通人群的研究结果表明，这些相互关系对于理解 ARHD 至关重要。 该项目的目标是分析最近完成的美洲印第安人服务利用、精神病学流行病学和风险/保护因素项目的数据，这是第一个针对 15 岁至 54 岁之间人工智能的大规模、基于人群的研究。该项目的目标如下：1）描述 2 个基于 15-54 岁人群的 AI 样本以及这些样本之间酒精使用流行病学的差异2 AI样本和代表美国一般人群的样本； 2) 对这些相同样本中酒精滥用和依赖的流行病学差异进行平行调查； 3) 扩大这一调查范围，探索与酗酒、滥用和依赖共存的药物使用、滥用和依赖的流行病学差异； 4) 描述与酒精使用、滥用和依赖共存的非物质使用精神疾病的流行病学差异； 5) 调查这两个人工智能部落以及这些部落与美国普通民众之间与饮酒、滥用和依赖相关的身体健康状况的流行病学差异。