Active Surveillance for Early Stage Prostate Cancer: Selection, Monitoring

早期前列腺癌的主动监测：选择、监测

• 批准号: 7113897
• 负责人: PETER R CARROLL
• 金额: $ 0.5万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-05-05 至 2007-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7113897
• 关键词: early /brief intervention /therapy; early diagnosis; meeting /conference /symposium; neoplasm /cancer classification /staging; neoplasm /cancer diagnosis; prostate neoplasms; travel

DESCRIPTION (provided by applicant): The goals of this conference are to: 1) Review the rationale for a program of active surveillance for men with apparent early stage prostate cancer; 2) Identify the most appropriate population of men who would be candidates for active surveillance; 3) Identify novel markers of the risk of progression which would aid in better patient selection; 4) Consider whether this patient population represents an opportunity for novel clinical trials; 5) Review results of such a treatment approach to date; 6) Identify the best type(s) of trials for such patients; 7) Build consensus on an appropriate plan to better study the important clinical and scientific questions raised in the symposium and attract new investigators into this field; and 8) Develop a prospective plan to encourage continuous communications among a network of experienced clinician scientists working in this field which may include, but is not limited to: an international disease registry, working group, tissue/urine and serum bank, and specific scientific collaborations. The target audience includes clinical investigators and basic scientists from a variety of disciplines: urology, oncology, pathology, and epidemiology. To accomplish these goals, we have designed a 1.5-day symposium to be held in San Francisco in the fall of 2006. Principal topics include: prostate cancer stage migration, natural history of early-stage prostate cancer, active surveillance and watchful waiting experience to date, patient selection, optimal surveillance regimens, psychosocial needs, novel biomarkers, novel clinical trials and patient advocacy. Sessions will be introduced by an expert moderator who will be followed by invited speakers who are authorities in their field. After each session, there will be a 45-minute panel discussion, which will foster exchange of ideas between speakers, moderators and the audience. Two breaks on day one, one break on day two and lunch on day one will allow more informal discussion. A poster session will encourage students, trainees, new investigators, and others interested in this field to attend.

描述（由申请人提供）：本次会议的目标是： 1) 审查对患有明显早期前列腺癌的男性进行主动监测计划的基本原理； 2) 确定最适合作为主动监测候选者的男性人群； 3）确定新的进展风险标志物，这将有助于更好地选择患者； 4) 考虑该患者群体是否代表了新的临床试验的机会； 5) 审查迄今为止这种治疗方法的结果； 6) 确定针对此类患者的最佳试验类型； 7）就适当的计划达成共识，以更好地研究研讨会上提出的重要临床和科学问题，并吸引新的研究人员进入该领域；和 8) 制定前瞻性计划，鼓励在该领域工作的经验丰富的临床科学家网络之间的持续沟通，其中可能包括但不限于：国际疾病登记处、工作组、组织/尿液和血清库以及具体的科学合作。目标受众包括来自泌尿学、肿瘤学、病理学和流行病学等各个学科的临床研究人员和基础科学家。 为了实现这些目标，我们设计了一个为期 1.5 天的研讨会，将于 2006 年秋季在旧金山举行。主要议题包括：前列腺癌分期迁移、早期前列腺癌的自然史、主动监测和观察等待经验日期、患者选择、最佳监测方案、社会心理需求、新型生物标志物、新型临床试验和患者倡导。会议将由专家主持人介绍，随后将邀请各自领域的权威人士进行演讲。 每场会议结束后，将举行 45 分钟的小组讨论，促进演讲者、主持人和观众之间的思想交流。 第一天两次休息、第二天一次休息和第一天午餐将允许进行更多非正式讨论。 海报会议将鼓励学生、实习生、新研究人员和其他对该领域感兴趣的人参加。