1st International Symposium on Wound Healing and Technology (WHAT I)

第一届伤口愈合与技术国际研讨会（WHAT I）

• 批准号: 7166108
• 负责人: Buddy D Ratner
• 金额: $ 2万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-07-10 至 2007-07-09
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7166108
• 关键词: meeting /conference /symposium; travel; wound healing

DESCRIPTION (provided by applicant): 1st International Symposium on Wound Healing And Technology The 1st International Symposium on Wound Healing And Technology (WHAT I), August 28-30, 2006, at the University of Washington will bring together scientists, physicians and engineers from academia and industry to overview a broad spectrum of technology advances in wound healing and the barriers that remain. WHAT I is significantly different from other wound-healing conferences in that this symposium will emphasize advanced approaches to wound healing using biomaterials, controlled release, tissue engineering, and other engineering methodologies. The conference will focus on the collaboration between materials scientists, engineers, biologists, and physicians involved in laboratory and clinical research to advance wound healing technology. Also, translational research will be spotlighted with a number of company presentations and audience participation by industrial scientists. Wound healing is a significant area for discussion because researchers and scientists still lack a clear fundamental understanding of chronic wound failures, despite decades of basic research. Even when underlying mechanisms to wound-healing are understood, significant problems persist, especially with patients suffering from chronic wounds and severe burns. Tissue-engineered constructs have entered the marketplace, but the costs are high, and the benefits limited. Compromised cosmetic outcomes are unfortunately the norm. Major challenges that remain are to induce tissue regeneration and the formation of pliable, mature dermis in full-thickness wounds and to control infection. Improved biocompatibility of materials used in wound care and tissue engineering is now possible. Communication and discussion of these new ideas is central to this meeting. Another powerful technology is the controlled-release of pharmaceutical agents. To date, only one prescription drug has been approved to induce healing of chronic wounds-despite more than 15 years of R&D and investigations of numerous candidate compounds. It is widely suspected that failure to deliver an effective dose at the correct time is a major underlying deficiency of wound-healing pharmaceuticals. Thus, WHAT I will bring clinician thought-leaders, basic academic scientists, and industrial leaders together to share bold ideas and foster cross-cutting collaboration. 1st International Symposium on Wound Healing And Technology Wound healing is a critical area for discussion because we still lack a clear fundamental understanding of chronic wound failures, despite decades of basic research. In order to advance not only our knowledge, but to develop materials and technology for the market, it is imperative that materials scientists, engineers, biologists, and physicians involved in laboratory and clinical research work together. Communication and discussion of these problems and new ideas for how we can address them are central to this meeting.

描述（由申请人提供）：第一届国际伤口愈合和技术研讨会是第一届国际伤口愈合和技术研讨会（我），2006年8月28日至30日，华盛顿大学将召集来自学术界和工业的科学家，医生和工程师，从而构成远景的范围，从而在伤口康复和障碍物中进行跨越的技术进步。我与其他伤口愈合会议的显着不同，因为该研讨会将强调使用生物材料，受控释放，组织工程和其他工程方法的先进方法进行伤口愈合。该会议将重点介绍材料科学家，工程师，生物学家和参与实验室和临床研究的医生之间的合作，以推进伤口愈合技术。此外，工业科学家的许多公司演讲和听众参与将备受瞩目。伤口愈合是一个重要的讨论领域，因为尽管经过数十年的基础研究，研究人员和科学家仍然对慢性伤口失败缺乏明确的基本了解。即使理解了伤口治疗的潜在机制，也存在重大问题，尤其是患有慢性伤口和严重烧伤的患者。组织工程结构已经进入市场，但成本很高，收益限制。不幸的是，化妆品结果折衷是规范。仍然存在的主要挑战是诱导组织再生以及在全厚度伤口中形成柔韧的，成熟的真皮并控制感染。现在可以改善伤口护理和组织工程中使用的材料的生物相容性。这些新想法的沟通和讨论是这次会议的核心。另一个强大的技术是药物剂的受控释放。迄今为止，尽管有超过15年的研发以及对众多候选化合物的调查，但仅批准了一种处方药来诱导慢性伤口疾病的愈合。人们普遍怀疑未在正确的时间输送有效剂量是伤口治疗药物的主要基础缺陷。因此，我将把临床医生思想领袖，基础学术科学家和工业领袖聚集在一起，共享大胆的想法并促进跨裁判合作。第一届国际伤口愈合和技术伤口愈合的研讨会是进行讨论的关键领域，因为尽管经过数十年的基础研究，我们仍然对慢性伤口失败的基本了解。为了不仅要促进我们的知识，还可以为市场开发材料和技术，必须将参与实验室和临床研究的材料科学家，工程师，生物学家和医生一起工作。这些问题的沟通和讨论以及我们如何解决这些问题的新想法是这次会议的核心。