Extramural Research Facilities Improvement Program

校外研究设施改进计划

• 批准号: 7877590
• 负责人: JAMES G FOX
• 金额: $ 1500万
• 依托单位: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-01-13 至 2014-01-14
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7877590
• 关键词: Accreditation; Animals; Beds; Biomedical Research; Caring; Ensure; Environment; Extramural Activities; Funding; Goals; House mice; Housing; Human Resources; Institutes; Laboratory Animals; Mission; Mus; Operative Surgical Procedures; Quarantine; Resources; Rodent; Source; System; United States National Institutes of Health; Vacuum; animal facility; animal resource; base; high standard; pathogen; programs; research facility

DESCRIPTION (provided by applicant): The Animal Resource Program at MIT represents a vital resource that is central to the various biomedical research missions of the Institute. This proposal seeks funds to renovate and equip the E25 animal facility in a manner consistent with current NIH and AAALAC standards. E25 is a critical component of the centralized MIT Animal Resource Program that encompasses 174,000 gsf of space housing 104,000 animals on a daily basis. The following specific aims are documented in this proposal. Specific Aim 1: To extensively renovate and expand an existing 25 year old animal facility, E25, comprising 16,430 gsf with 11,105 nsf of usable housing, procedural, surgical, and quarantine space to allow continuation of biomedical research involving multiple species of animals. Specific Aim 2: To equip E25 with a tunnel washer, bedding dispenser and vacuum disposal system, ventilated rodent housing and mouse transfer stations, to maximize space and personnel efficiency and protection of mice from acquiring infectious murine pathogens. The specific improvements are directly related to the long term goal of MIT's Animal Resource Program, which is to provide the best possible environment for scientific inquiry supported by NIH and other sources, concurrently maintain AAALAC accreditation, and ensure the highest standards of humane care and use of laboratory animals.

描述（由申请人提供）：麻省理工学院的动物资源计划代表了研究所各种生物医学研究任务至关重要的重要资源。该提案寻求以符合当前NIH和AAAALAC标准一致的方式翻新和装备E25动物设施的资金。 E25是集中式MIT动物资源计划的关键组成部分，该计划每天涵盖174,000 GSF的空间外壳。本提案中记录了以下特定目标。 具体目的1：为E25进行广泛翻新和扩展现有的25年动物设施，其中包括16,430 GSF，其中包括11,105 NSF的可用住房，程序性，外科手术和隔离空间，以继续生物医学研究，涉及多种动物。 特定目标2：为E25配备隧道洗衣机，床上用品分配器和真空处理系统，通风的啮齿动物外壳和小鼠转移站，以最大程度地提高空间和人员效率，并保护小鼠免受感染性鼠病原体的获取。 具体的改进与MIT动物资源计划的长期目标直接相关，该计划是为NIH和其他来源支持的科学探究提供最佳环境，同时维持AAALAC认证，并确保人道护理的最高标准和实验室动物的使用。