Biomedical Informatics Training Program

生物医学信息学培训计划

• 批准号: 6782648
• 负责人: Pierre Baldi
• 金额: $ 107.55万
• 依托单位: UNIVERSITY OF CALIFORNIA-IRVINE
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-07-01 至 2007-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6782648
• 关键词: Biomedical; Informatics; Training; Program

DESCRIPTION (provided by applicant): Genome sequencing projects are rapidly providing the genetic blueprint of organisms across the kingdoms of life. Biologists, who traditionally have focused their work on single genes and proteins, can now study genes and proteins across multiple organisms and conditions. Thus, in various forms, genomic sequences are catalyzing our abilities to understand biological systems at levels never before possible. However, new genomic technologies are generating overwhelming amounts of data that must be processed and analyzed. These massive amounts of data have created a critical need for theoretical, algorithmic, software, and hardware advances in storing, retrieving, networking, processing, modeling, analyzing, and visualizing biological and medical information. These needs are inspiring new concepts in computer science, such as genetic algorithms, artificial neural networks, computer viruses, synthetic immune systems, DNA computing methods, artificial life, and hybrid DNA gene chips. Because of these developments, computer science applications in the fields of biology and medicine showcase the latest advances in core computer science from hardware to software, from algorithms to databases, and from theory to user interfaces. This cross-fertilization has enriched both fields and will continue to do so in the coming decades. However, interdisciplinary graduate programs in bioinformatics remain scarce and the pool of individuals with training in both computational and biomedical sciences is still exceedingly small. To meet this challenge, successful training programs in biomedical informatics have been developed at UCI. In particular, a training emphasis in bioinformatics has been established in the Information and Computer Science (ICS) Department; and, an interdisciplinary graduate training program in biomedical informatics has been formed with training faculty from ICS and the College of Medicine. These programs have been funded by University and Federal seed grants. Largely because of the success of these programs in increasing interdisciplinary research and training, a campus-wide Institute for Genomics and Bioinformatics (IGB) was established earlier this year, and bioinformatics training tracks have been developed in other academic units. The Biomedical Informatics Program proposed here will consolidate these accomplishments into a comprehensive campus-wide training program administered by the IGB, and facilitate increased training and research interactions among the clinical and basic science researchers at UCI.

描述（由申请人提供）： 基因组测序项目正在迅速提供的遗传蓝图 生命王国的生物。 传统上有生物学家 将他们的工作集中在单基因和蛋白质上，现在可以研究基因， 多种生物和条件的蛋白质。因此，以各种形式 基因组序列正在促进我们了解生物学的能力 从未有过的级别的系统。但是，新的基因组技术是 生成必须处理和分析的大量数据。 这些大量数据已经对理论， 算法，软件和硬件进步，用于检索，检索， 网络，处理，建模，分析和可视化生物学和 医疗信息。这些需求激发了计算机中的新概念 科学，例如遗传算法，人工神经网络，计算机 病毒，合成免疫系统，DNA计算方法，人造生命和 杂交DNA基因芯片。由于这些发展，计算机科学 生物学和医学领域的应用展示了最新的 核心计算机科学从硬件到软件的进步，算法 到数据库以及从理论到用户界面。这种交叉施肥具有 这两个领域都充实了，并将在未来几十年中继续这样做。 但是，生物信息学的跨学科研究生课程仍然很少 以及在计算和生物医学中接受培训的个体库 科学仍然非常小。 为了应对这一挑战，生物医学信息学的成功培训计划 已在UCI开发。 特别是在 在信息和计算机科学中已经建立了生物信息学 （ICS）部门；而且，跨学科的研究生培训计划 生物医学信息学是由ICS和 医学院。这些计划由大学和联邦资助 种子赠款。很大程度上是因为这些计划在增加 跨学科研究与培训，范围内的基因组学研究所 和生物信息学（IGB）是今年早些时候建立的，生物信息学 在其他学术部门已经开发了培训轨道。生物医学 这里提出的信息学计划将把这些成就巩固到 IGB管理的全面校园培训计划， 促进临床和基本的增加培训和研究相互作用 UCI的科学研究人员。