Mid Career Mentoring Award In Patient-Oriented Research

以患者为导向的研究中的职业生涯中期指导奖

• 批准号: 6671877
• 负责人: MARK STEVEN LACHS
• 金额: $ 12.21万
• 依托单位: WEILL MEDICAL COLL OF CORNELL UNIV
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-09-01 至 2008-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6671877
• 关键词: alcoholic beverage consumption; behavioral /social science research tag; cognition disorders; functional ability; health behavior; human old age (65+); human subject; interview; mental health epidemiology; patient oriented research; psychological aspect of aging

DESCRIPTION (provided by applicant): This application proposes use of the NIA mid-career award in patient-oriented research to create and sustain a mentoring program for aspiring aging researchers at the Weill Medical College of Cornell University led by Dr. Mark Lachs. Dr. Lachs is a geriatrician and clinical epidemiologist with expertise in the areas of elder mistreatment, protective services, and functional status. He is also Directs the Cornell Center for Aging Research and Clinical Care (CCARCC), an institution wide entity seeded by an NIA Academic Leadership Award and formalized by the Dean in 2000. CCARCC's infrastructure will assist in identifying mentored trainees, provide additional resources to them (e.g., through its pilot grant program), and formally evaluate Dr. Lachs' K24 program through an external advisory committee led by Dr. William Hazzard. Two new patient-oriented research projects are proposed in the area of elder self-neglect (ESN). The specific aims of these are: (1) to estimate the contribution of executive dysfunction to self-care behaviors that may precede ESN, and (2) to determine if alcohol consumption is an risk factor for ESN. These studies hypothesize that ESN is a continuum of progressively more egregious low self-care states. ESN as chosen as a content area because (a) it is a multi-factorial syndrome likely to attract trainees with interests from diverse fields (e.g., geriatric medicine and psychiatry, neuropsychology, nutrition, alcohol, and medicalethics), (b) it is prevalent but studied despite substantial mortality and indignity, and (c) Cornell has an unusual depth of expertise (and potential mentees) in geriatric psychiatry in the form of the Cornell Geriatric Psychiatry Institute headed by George Alexopoulos. Preliminary data on depression and ESN are provided. Strengths of the candidate include his formal training in research methodology as an RWJ Clinical Scholar at Yale, his history of academic productivity and continuous NIH funding including an active RO1 in the area of crime and health in older people, and an early track record of mentoring junior trainees at all levels. Strengths of the institution include the resources of CCARCC, several aging related Centers at Cornell from which to garner potential mentees, the availability of divisional resources to "protect" promising trainees in the critical period between fellowship and initial extramural funding, and a divisional co-chief structure that can insulate the candidate from undue administrative and clinical burdens should this application be successful.

描述（由申请人提供）：本申请建议将 NIA 职业生涯中期奖用于以患者为导向的研究，为马克·拉克斯 (Mark Lachs) 博士领导的康奈尔大学威尔医学院有抱负的老龄化研究人员创建和维持一个指导计划。拉克斯博士是一位老年病学家和临床流行病学家，在老年人虐待、保护服务和功能状态方面拥有专业知识。他还领导康奈尔大学老龄化研究和临床护理中心 (CCARCC)，该中心是一个机构范围内的实体，由 NIA 学术领导奖培育，并于 2000 年由院长正式成立。CCARCC 的基础设施将协助确定受指导的学员，为他们提供额外的资源（例如，通过其试点资助计划），并通过 William Hazzard 博士领导的外部咨询委员会正式评估 Lachs 博士的 K24 计划。在老年人自我忽视（ESN）领域提出了两个新的以患者为导向的研究项目。这些研究的具体目标是：(1) 估计执行功能障碍对可能发生 ESN 之前的自我护理行为的影响，以及 (2) 确定饮酒是否是 ESN 的危险因素。这些研究假设 ESN 是一个逐渐变得更加严重的低自理状态的连续体。选择 ESN 作为内容领域是因为 (a) 它是一种多因素综合症，可能会吸引来自不同领域（例如老年医学和精神病学、神经心理学、营养学、酒精和医学伦理学）感兴趣的学员，(b) 它是普遍存在，但尽管死亡率和侮辱性很高，但仍进行了研究，并且（c）康奈尔大学在老年精神病学方面拥有非同寻常的深度专业知识（和潜在的受训者），以康奈尔大学的形式老年精神病学研究所由乔治·阿莱克索普洛斯领导。提供了有关抑郁症和 ESN 的初步数据。候选人的优势包括他作为耶鲁大学 RWJ 临床学者在研究方法方面的正式培训、他的学术生产力和持续的 NIH 资助历史，包括在老年人犯罪和健康领域的活跃 RO1，以及早期的指导记录各级初级学员。该机构的优势包括 CCARCC 的资源、康奈尔大学的几个与老龄化相关的中心（可从中吸引潜在的受训者）、在奖学金和初始校外资助之间的关键时期提供部门资源以“保护”有前途的受训者，以及部门合作如果申请成功，可以使候选人免受不当行政和临床负担的主要结构。