Child Abuse, HIV Risks and Reproductive Outcomes

虐待儿童、艾滋病毒风险和生殖结果

• 批准号: 6861832
• 负责人: TAMRA B LOEB
• 金额: $ 7.71万
• 依托单位: UNIVERSITY OF CALIFORNIA LOS ANGELES
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-03-01 至 2007-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6861832
• 关键词: HIV infections; behavioral /social science research tag; child abuse; crime victims; culture; data management; depression; disease /disorder proneness /risk; ethnic group; high risk behavior /lifestyle; human data; immigrant; information systems; multilingualism; outcomes research; public health; reproduction; sex abuse; sex behavior; sign /symptom; statistics /biometry

DESCRIPTION (provided by applicant): This RO3 application seeks two years of funding for secondary analyses to: (1) combine two community based multi-ethnic samples of women in Los Angeles County; the Women and Family Project (NIMH48269), a sample of 318 HIV-positive and 172 HIV-negative women, and the Los Angeles Women's Study (NIMH 33603), consisting of 905 HIV-negative women; (2) construct a child sexual abuse severity index (CSASI) of 6 dimensions of child sexual abuse experiences; and (3) examine the differential effects of the CSASI on HIV serostatus, HIV related sexual risk behaviors, reproductive outcomes, depressive symptoms, and adult sexual revictimization in 318 HIV-positive and 1077 HIV-negative African American (N=460), Latina (N=449), and European American (N=453) Los Angeles County women. The two studies contain a comparable assessment of child sexual abuse (CSA) experiences, HIV risks, and reproductive outcomes. The CSASI will be developed using Principal Component Analysis to assess the differential effects of each CSA dimension on adverse outcomes. Guided by aspects of the Life Course Model, characteristics of women with different levels of CSA severity will be identified with bivariate analyses of correlations, two-way tables, marginal regression and analysis of variance. Other factors including HIV serostatus, HIV-related sexual risk taking, sexual revictimization, depressive symptoms and reproductive outcomes, will be examined with bivariate analyses and multivariate modeling. This proposal unites the literature on HIV risk, child sexual abuse, and reproductive outcomes. Research has historically treated these public health concerns as separate fields of study. The accumulation of literature and coding manuals as well as the CSASI index will be available to other researchers through the UCLA AIDS Institute Website. Results will be used to increase knowledge of how HIV risks, the severity of CSA, and reproductive outcomes are associated for women.

描述（由申请人提供）：此RO3申请寻求两年的二级分析资金，以：（1）结合洛杉矶县的两个基于社区的妇女多种族样本；妇女和家庭项目（NIMH48269），318个HIV阳性和172名HIV阴性妇女的样本，以及洛杉矶妇女研究（NIMH 33603），由905名HIV-Sangement妇女组成； （2）建造一个儿童性虐待经历的6个维度的儿童性虐待严重性指数（CSASI）； （3）检查CSASI对318 HIV阳性和1077 HIV-Pergation American American Americation的CSASI对HIV血清，与HIV相关的性风险行为，生殖症状，抑郁症状和成人性重复的影响的差异作用（N = 460），拉丁裔（N = 449）和欧洲妇女（N = 449）和县（N = 453）。这两项研究包括对儿童性虐待（CSA）经历，艾滋病毒风险和生殖结果的可比评估。 CSASI将使用主成分分析开发，以评估每个CSA维度对不良结果的差异效应。在生活课程模型的各个方面的指导下，将通过相关性，双向表，边际回归和方差分析的双变量分析来确定具有不同CSA严重程度的女性的特征。其他因素将通过双变量分析和多变量建模来检查，包括HIV血清血清相关的性风险服用，性复兴，抑郁症状和生殖结果。该提案将有关艾滋病毒风险，儿童性虐待和生殖结果的文献团结在一起。历史上，研究将这些公共卫生问题视为单独的研究领域。文学和编码手册的积累以及CSASI指数将通过UCLA AIDS Institute网站提供给其他研究人员。结果将用于增加对艾滋病毒风险，CSA的严重程度和生殖结果如何与女性相关的知识。