Intervention for HIV+ Adults With Childhood Sexual Abuse

对患有儿童期性虐待的艾滋病毒成人进行干预

• 批准号: 7061909
• 负责人: NATHAN B HANSEN
• 金额: $ 17.96万
• 依托单位: YALE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-01-01 至 2010-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7061909
• 关键词: AIDS education /prevention; HIV infections; behavioral /social science research tag; child abuse; clinical research; clinical trials; cognitive behavior therapy; high risk behavior /lifestyle; human immunodeficiency virus; human subject; human therapy evaluation; interview; patient oriented research; psychological shock; questionnaires; sex abuse; sex behavior; therapy design /development; AIDS education /prevention; HIV infections; behavioral /social science research tag; child abuse; clinical research; clinical trials; cognitive behavior therapy; high risk behavior /lifestyle; human immunodeficiency virus; human subject; human therapy evaluation; interview; patient oriented research; psychological shock; questionnaires; sex abuse; sex behavior; therapy design /development

DESCRIPTION (provided by applicant): This application presents a program of research and training that focuses on integrating HIV-prevention strategies into mental health treatments for trauma. Specifically, the proposed project aims to develop and pilot test an intervention for HIV-positive adult survivors of childhood sexual abuse (CSA) who are sexually active and exhibit psychiatric distress related to trauma. The widespread prevalence of CSA among HIV+ adults is concerning as CSA has been linked to poor mental health, substance abuse, HIV risk behavior, and poor treatment adherence and outcome. The training objectives are to develop the PI's expertise in: (1) developing culturally sensitive empirically supported mental health treatments for trauma and CSA, (2) integrating HIV-prevention strategies into mental health treatments for trauma and CSA, and (3) learning advanced quantitative data analytic skills for longitudinal data and outcome analysis. Drs. Kathleen Sikkema and John Briere will supervise the training. The primary goals of the proposed project are to: (1) develop a 16 session individual cognitive-behavioral intervention for HIV+ adults with a history of CSA based on self- trauma theory and tailored to meet the needs of those living with HIV; (2) pilot test this intervention with a sample of 80 participants, 40 who will be randomized into an initial treatment condition followed by a four- month follow-up, and 40 who will be randomized into a four-month waitlist condition followed by treatment with the study intervention; and (3) evaluate the intervention's ability to reduce distress and HIV transmission risk behavior, and collect estimates of effect size for future research. This award will result in a intervention that integrates HIV-prevention strategies into mental health treatment for HIV-positive adults who have experienced CSA, a group with elevated risk for HIV-transmission behavior, that can be evaluated in a randomized, controlled intervention trial. The award will also support the PI's long term goal of integrating HIV-prevention strategies into the mental health care of vulnerable populations, such as survivors of trauma.

描述（由申请人提供）：本申请提出了一项研究和培训计划，重点是将艾滋病毒预防策略纳入创伤的心理健康治疗。具体而言，拟议的项目旨在开发和试点测试对儿童性虐待的艾滋病毒阳性成人幸存者（CSA）的干预，他们具有性活跃并表现出与创伤有关的精神病困扰。艾滋病毒+成年人中CSA的普遍流行与CSA有关，与精神健康不良，药物滥用，艾滋病毒风险行为以及治疗依从性和结果不佳有关。培训目标是在以下方面发展PI的专业知识：（1）为创伤和CSA开发具有文化敏感的经验支持的心理健康治疗方法，（2）将HIV预防策略整合到Trauma和CSA的心理健康治疗中，以及（3）学习高级数据分析技能，以备久数据和结果分析。博士。凯瑟琳·西克马（Kathleen Sikkema）和约翰·布里埃（John Briere）将监督培训。拟议项目的主要目标是：（1）针对基于自我创伤理论的CSA史，为具有CSA病史的艾滋病毒+成年人开发16个会话，并为满足HIV患者的需求而定制； （2）试点测试该干预措施，包括80名参与者的样本，40名将被随机分为初始治疗条件，然后进行四个月的随访，而40名将被随机分为四个月的候补列表条件，然后进行研究干预； （3）评估干预措施减少困扰和艾滋病毒传播风险行为的能力，并收集对未来研究的影响大小的估计。该奖项将导致一项干预措施将艾滋病毒预防策略纳入经历过CSA的艾滋病毒阳性成年人的心理健康治疗，这是一个CSA，这是一个具有艾滋病毒传播行为风险升高的小组，可以在随机，对照干预试验中进行评估。该奖项还将支持PI的长期目标，即将艾滋病毒预防策略纳入脆弱人群的心理保健，例如创伤的幸存者。