Treatment Effectiveness for PTSD in Young Children

幼儿创伤后应激障碍 (PTSD) 的治疗效果

• 批准号: 6863355
• 负责人: MICHAEL S SCHEERINGA
• 金额: $ 20.05万
• 依托单位: TULANE UNIVERSITY OF LOUISIANA
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-03-03 至 2007-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6863355
• 关键词: accidents; behavioral /social science research tag; child mental disorders; clinical research; cognitive behavior therapy; domestic violence; dyadic interaction; early experience; human subject; human therapy evaluation; injury; interview; longitudinal human study; middle childhood (6-11); outcomes research; parent offspring interaction; patient oriented research; posttraumatic stress disorder; psychological adaptation; psychological shock; questionnaires; stress management

DESCRIPTION (provided by applicant): The aims of this research plan are (1) to demonstrate the successful adaptation and implementation of a theoretically-based manualized cognitive-behavioral treatment (CBT) for preschool-age children (3-6 years) with PTSD, and (2) to demonstrate that PTSD symptoms in the children and level of distress in the parents can be meaningfully reduced. No studies have attempted to show effectiveness of any psychosocial treatment in preschool children who have suffered interpersonal traumas, except for sexual abuse. This application is meant to fill that gap. The manualized protocol utilizes the CBT techniques of graded exposure, anxiety management training, and developing a coherent narrative of the trauma free of cognitive distortions. This is combined with parent-child relational treatment techniques focused on supportive therapy, parent management training, and enhancement of parent compliance. The subjects will be heterogeneous in regard to type of trauma, including children who have witnessed severe domestic violence, and those that have suffered acute accidental injuries. In Phase 1, 8 children with PTSD will be recruited and enrolled in the treatment. We will use systematic checklists, consensus panel reviews, and expert consultation from individual cases to guide the developmental adaptation and implementation of this intervention. Multiple indices of success will be assessed including therapist adherence, child compliance, parent compliance, parent reluctance, and parent acceptance. Repeated feedback mechanisms will be used to revise the manual/protocol to eventually achieve 90% completion of CBT tasks and 90% therapist adherence to the manual. In Phase 2, 38 children with PTSD will be recruited and randomized for intervention into either immediate treatment or a 12-week wait-list condition to control for the passage of time. We will measure the change in children's symptoms, and change in parents' symptoms and distress levels, in addition to the adaptation and implementation measures from Phase 1.

描述（由申请人提供）：该研究计划的目的是（1）证明针对PTSD的学龄前儿童（3-6岁）的理论上基于理论上的手动认知行为治疗（CBT）的成功适应和实施，并且（2）证明了PTSD症状，可以证明PTSD的症状，并可以在父母的层次上进行痛苦的症状。没有研究试图表明对遭受人际创伤的学龄前儿童进行任何心理社会治疗的有效性，但性虐待除外。此应用程序旨在填补该空白。手动协议利用了分级暴露，焦虑管理培训的CBT技术，并开发了没有认知扭曲的创伤的连贯叙述。这与父母亲子关系治疗技术相结合，重点是支持治疗，父母管理培训和提高父母依从性。这些受试者在创伤类型方面将是异质的，包括目睹了严重家庭暴力的儿童以及遭受急性意外伤害的孩子。在第1阶段，将招募8名PTSD儿童并参与治疗。我们将使用系统的清单，共识小组审查以及各个案例的专家咨询来指导此干预的发展适应和实施。将评估多个成功指标，包括治疗师的遵守，父母遵守，父母不愿和父母接受。重复的反馈机制将用于修改手动/协议，以最终完成90％的CBT任务完成，并遵守90％的治疗师。在第2阶段中，将招募38名PTSD儿童并随机分组以立即治疗或为期12周的等待名单，以控制时间的流逝。除了从第1阶段的适应和实施措施外，我们还将衡量儿童症状的变化以及父母症状和困扰水平的变化。