Training Program in Free Radical and Radiation Biology

自由基和放射生物学培训计划

• 批准号: 7119831
• 负责人: LARRY OBERLEY
• 金额: $ 3.14万
• 依托单位: UNIVERSITY OF IOWA
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-07-01 至 2009-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7119831
• 关键词: Training; Program; Free; Radical; Radiation

EXCEED THE SPACE PROVIDED. The University of Iowa Training Program in Free Radical and Radiation Biology is oriented around six key goals for education in preparation of trainees for a career in free radical and radiation biology: 1) To impart e fundamental understanding of the subject matter of radiation biology, free radical biology, and cancer biology; 2) To provide trainees with the opportunity to achieve proficiency in the radiation biology, free radical biology, and molecular oncology disciplines leading to successful careers in cancer research; 3) To structure research experience for trainees that includes the development of a research proposal, execution of a research project, and evaluation of these results for submission in peer-reviewed publications; 4) To offer trainees experience in learning the necessary knowledge and skills to do collaborative research with faculty in clinical and basic science departments; 5) To provide trainees with critical knowledge of the structure of science and essential skills in both oral and written scientific communication; and 6) To encourage trainees to implement innovative approaches in a "real world" environment to test explicit hypotheses about the mechanisms and consequences of radiobiological and free radical phenomena. With this application, we are proposing to continue to support three predoctoral trainees per year and also to phase in the additional support of postdoctoral trainees. We propose to support one postdoctoral trainee in the first year, two in the second, and three in years 3-5. We have an internationally recognized faculty with consistent involvement in nationally recognized radiobiology and free radical research projects, program projects, individual research awards, and The University of Iowa Cancer Center. We propose to have 10 mentors in the Training Program, 4 from the Department of Radiation Oncology and one each from the Departments of Internal Medicine, Pathology, Surgery, Anatomy and Cell Biology, Exercise Science, and Chemistry. Education for our trainees involves one-on-one mentoring by faculty members, working on cancer- related nationally recognized research projects, presenting work and receiving feedback at national meetings, plus formal course work offered by the department and the other excellent resources at The University of Iowa. Formal coursework includes classes in radiation, free radical, and cancer biology. The faculty, fellows, and students form a critical mass for providing a provocative environment for seminars, journal clubs, and informal discussion. Research being pursued goes from the benchtop to the clinic. Communication, both verbal and written, is stressed in the Training Program, so that the science that is done can be communicated to other scientists. We believe this Training Program has all the ingredients necessary to produce the needed high quality scientists in free radical and radiation biology who will work in cancer research. PERFORMANCE SITE ========================================Section End===========================================

超过提供的空间。爱荷华大学自由激进和放射生物学的培训计划围绕教育的六个关键目标，为受训者做好了自由基和放射生物学职业的准备：1）对放射生物学，自由基生物学和癌症生物学的主题进行基本了解； 2）为受训者提供了熟练掌握辐射生物学，自由基生物学和分子肿瘤学学科的机会； 3）为受训者构建研究经验，包括制定研究建议，执行研究项目以及对这些结果的评估以在同行评审的出版物中提交； 4）为学员提供学习必要的知识和技能的经验，以与临床和基础科学部门的教师进行协作研究； 5）为学员提供对口头和书面科学交流的科学和基本技能结构的批判性知识； 6）鼓励学员在“现实世界”环境中实施创新的方法，以检验有关放射生物学和自由基现象的机制和后果的明确假设。通过此申请，我们建议继续支持每年三名托管前学员，并为博士后学员提供额外支持。我们建议在第一年支持一名博士后学员，第二年为两名，在3 - 5年中支持三个。我们拥有国际公认的教师，并始终参与了国家认可的放射生物学和自由基研究项目，计划项目，个人研究奖和爱荷华大学癌症中心。我们建议在培训计划中有10位导师，其中4位来自放射线肿瘤学系，每人来自内科，病理，手术，解剖学和细胞生物学，运动科学和化学的部门。我们的学员的教育涉及教职员工的一对一指导，从事与癌症相关的全国认可的研究项目，在国家会议上提出工作和接收反馈，以及该系和爱荷华大学的其他优秀资源提供的正式课程工作。正式的课程包括辐射，自由基和癌症生物学的课程。教职员工，研究员和学生构成了为研讨会，期刊俱乐部和非正式讨论提供挑衅性环境的关键群众。进行的研究从台式台上到诊所。培训计划中强调了言语和书面的交流，因此可以将所做的科学传达给其他科学家。我们认为，该培训计划具有生产将在癌症研究中工作的自由基和放射生物学中所需的高质量科学家所需的所有成分。表演站点=============================================================================================