Micro Sensor for Cochlear and Middle Ear Implant Systems

用于耳蜗和中耳植入系统的微传感器

基本信息

批准号：
6831705
负责人：
WEN H KO
金额：
$ 22.95万
依托单位：
CASE WESTERN RESERVE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2003
资助国家：
美国
起止时间：
2003-12-05 至 2006-11-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/6831705
关键词：
auditory ossicles bioengineering /biomedical engineering biomedical equipment development biosensor device cochlear implants cochlear microphonic potentials hearing hearing aids medical implant science middle ear sound perception temporal bone vibration perception

项目摘要

DESCRIPTION (provided by applicant): An exploratory research is proposed to develop micro-sensors that can be used as implant microphones to sense the sound vibration of the middle ear structure and to convert it into high quality electrical signals for the input of implant cochlear or middle-ear hearing systems. The proposed project will bring together the medical and engineering investigators to integrate the expertise in hearing physiology, sensor design, micro-machining technology, and micro-electronics with the aims: (1) to study novel sensor mechanisms that can function in the middle ear chamber without packaging and presents minimum loading [less than 10 mg] to the ossicles; (2) to develop design and fabrication processes of the implantable sensor that can detect the sound vibration of ossicles without alter the structure and does not require critical positioning of the sensor in the middle ear chamber; (3) to design and fabricate the micropowered electronics circuit to amplify the sound signal to a level that can be coupled to the input of the existing cochlear implant system or can be connected to an implant middle ear actuator to provide adequate hearing aid function; and (4) to evaluate the prototype sensor and the bio-electronic microphone in the laboratory and in the temporal bone expedients to assess the feasibility of pursuing the future development of totally implantable cochlear system and middle ear hearing device. When the result of this exploratory study justifies, a continuation proposal will be submitted for further study to develop and fabricate the clinical version of micro-sensors and to evaluate them in animals as well as selected clinical cases for the development of totally implantable cochlear systems or middle ear hearing devices.

描述（由申请人提供）：提出了一项探索性研究，以开发可用作植入麦克风的微传感器，以感知中耳结构的声音振动，并将其转换为高质量的电信号，以输入植入物耳蜗或中耳听力系统。拟议的项目将汇集医学和工程研究人员，以整合听力生理学，传感器设计，微型播放技术和微电子电脑的专业知识，目的是：（1）研究可以在中耳腔中起作用的新型传感器机制，而无需包装，而无需包装，而无需包装和呈现最小的载荷[小于10 mg]。（2）开发可植入的传感器的设计和制造过程，这些传感器可以检测到没有改变结构的ossicles的声音振动，并且不需要在中耳腔室中传感器的临界定位；（3）设计和制造微型电子电路，以将声音信号放大到可以耦合到现有的耳蜗植入物系统输入的水平，或者可以连接到植入物中耳执行器以提供足够的助听器功能；（4）评估实验室中的原型传感器和生物电子麦克风以及颞骨的权宜之计，以评估追求完全植入的可植入的耳蜗系统和中耳听力设备的未来开发的可行性。当这项探索性研究的结果是合理的时，将提交一项进一步研究的延续建议，以开发和制造微传感器的临床版本，并在动物中评估它们，并在动物中评估它们，以开发完全植入的可植入的耳蜗系统或中耳听力设备。