Cold Spring Harbor Conference The Ubiquitin Family

冷泉港会议泛素家族

• 批准号: 6738010
• 负责人: TERRI I. GRODZICKER
• 金额: $ 0.9万
• 依托单位: COLD SPRING HARBOR LABORATORY
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-04-01 至 2006-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6738010
• 关键词: angiogenesis; biological signal transduction; bone metabolism; cartilage metabolism; cell death; communicable diseases; endopeptidases; enzyme activity; enzyme inhibitors; inflammation; meeting /conference /symposium; neoplasm /cancer; neural degeneration; proteolysis; travel

DESCRIPTION (provided by Applicant) Proteolysis has emerged as a major fundamental mechanism of many biological processes ranging from development to apoptosis. Traditionally, studies of proteolytic enzymes have focused heavily on biochemical mechanisms, structure, and inhibition, and most meetings on proteolysis have reflected this interest. However, as new methods have emerged for the study of protease function in vivo, there are an increasing number of laboratories involved in studies of protease biology. The objective of the Third Meeting on the Biology of Proteolysis is to bring together investigators of protease biology with those who study the biochemical and structural properties of these enzymes. Clearly, given the similarities between proteolytic systems involved in distinct biological processes, this meeting presents an exciting opportunity for participants to learn about recent developments that will be relevant to their own research. The program will include eight sessions covering the most prominent biological systems involving proteolysis, which will be led by two outstanding and well-known investigators in these areas. With the exception of overview talks presented by the session chairs, all of the talks and posters to be presented will be selected from submitted abstracts, and most of the talks will be given by students, postdoctoral fellows and other younger investigators. It is expected that more than 250 scientists will attend. Of these, over half are likely to be graduate students and postdoctoral fellows. The subsequent meetings (2003 and 2005) will follow a similar format which will include topics that are highly relevant to the current research at the time of the meeting.

描述（由申请人提供） 蛋白水解已成为许多生物学的主要基本机制 从发育到凋亡的过程。 传统上，研究 蛋白水解酶已重点关注生化机制，结构， 和抑制作用以及大多数关于蛋白水解的会议都反映了这一兴趣。 但是，随着新方法的出现，用于研究蛋白酶功能 体内，参与研究的实验室越来越多 蛋白酶生物学。 关于第三次会议的有关生物学的目的 蛋白水解是将蛋白酶生物学的研究人员与那些 研究这些酶的生化和结构特性。 显然，鉴于涉及的蛋白水解系统的相似性 截然不同的生物过程，这次会议带来了激动人心的机会 让参与者了解与 他们自己的研究。 该计划将包括八个涵盖最多的会议 涉及蛋白水解的著名生物系统将由两个领导 这些领域的杰出和著名的研究人员。 除了例外 会议椅，所有谈判和 要展示的海报将从提交的摘要中选择，大部分 会谈将由学生，博士后研究员和其他年轻人进行 调查人员。 预计将有250多名科学家参加。 的 这些超过一半可能是研究生和博士后研究员。 随后的会议（2003年和2005年）将遵循类似的格式 将包括与当前研究高度相关的主题 会议的时间。