Hereditary Multiple Exostoses:Insights Into Pathogenesis

遗传性多发性外生骨疣：发病机制的见解

• 批准号: 7059235
• 负责人: DAN E WELLS
• 金额: $ 0.5万
• 依托单位: UNIVERSITY OF HOUSTON
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-09-30 至 2006-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7059235
• 关键词: chondrodystrophy; disease /disorder etiology; meeting /conference /symposium; pathologic process; travel

DESCRIPTION (provided by applicant): The primary objective of the conference is to establish a clinical and research community devoted to understanding and treating Hereditary Multiple Exostosis (HME). This will be accomplished by bringing together basic researchers and orthopedic physicians, medical geneticists, and families with HME. The meeting will facilitate discussion and collaboration both among and between all groups, accelerating the integration of current knowledge and identifying new areas with future research potential. The three day conference to be held at the Shriners Hospital for Children in Houston, TX is scheduled for November 3, 4, 5, 2005, and will bring together about 40-45 full participants (including 30-40 speakers and 5-10 nonspeaking discussants). The non-speaking discussants are other experts in the field of HME and bone development and disease and members of the MHE Coalition, a co-sponsor of the conference. All conference full participants will be involved in the entire conference and will be required to attend all sessions. The last day of the conference will be expanded to include local medical students, residents, and scientists from other fields as well as individuals and families with HME. There will be 7 scientific sessions including: Introduction/Clinical Genetics; Medical/Orthopedic considerations; EXT Function/ Biochemistry; Non-vertebrate Models; Bone Development I; Bone Development II; Exostoses/Cancer; Non-bone phenotypes/EXT-like genes; Related Bone diseases; HME Workshop. Each session will have three to four invited speakers who will present 20 minute talks followed by 10 minutes of discussion. We will encourage all speakers to generalize their findings with regard to its biological context and significance so that it will be accessible to all participants. Informal discussion will also be encouraged outside of the formal sessions during meals and after the afternoon sessions. It is hoped that these discussions will promote new interactions and collaborations between participants.

描述（由申请人提供）：会议的主要目的是建立一个致力于理解和治疗遗传性多重外神经局（HME）的临床和研究社区。这将通过将基础研究人员和骨科医师，医学遗传学家和HME家庭汇集在一起​​来实现。这次会议将促进所有小组之间和之间之间的讨论和协作，从而加快当前知识的整合并确定具有未来研究潜力的新领域。预定在德克萨斯州休斯敦的Shriners儿童医院举行的为期三天的会议定于2005年11月3日，4日，5日，将召集约40-45名全面参与者（包括30-40名演讲者和5-10名非言语讨论者）。非讲话的讨论者是HME和骨骼发展和疾病领域的其他专家，以及会议的共同赞助商MHE联盟的成员。所有会议的完整参与者将参与整个会议，并将被要求参加所有会议。会议的最后一天将扩展到包括其他领域的当地医学生，居民和科学家以及HME的个人和家庭。将有7个科学会议，包括：引言/临床遗传学；医疗/骨科考虑； EXT功能/生物化学；非魔力模型；骨发育i；骨发育II；外遗体/癌症；非骨表型/ext样基因；相关骨骼疾病； HME研讨会。每个会议将有三到四个受邀演讲者，他们将进行20分钟的演讲，然后进行10分钟的讨论。我们将鼓励所有发言人在其生物学背景和意义上概括他们的发现，以便所有参与者都可以访问它。在饭菜期间和下午会议之后，还将鼓励非正式的讨论在正式会议之外。希望这些讨论将促进参与者之间的新互动和合作。