TRAINING PROGRAM IN QUANTITATIVE BIOLOGY AND PHYSIOLOGY

定量生物学和生理学培训计划

• 批准号: 6919142
• 负责人: KENNETH R LUTCHEN
• 金额: $ 20.01万
• 依托单位: BOSTON UNIVERSITY (CHARLES RIVER CAMPUS)
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-07-01 至 2006-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6919142
• 关键词: TRAINING; PROGRAM; QUANTITATIVE; BIOLOGY; PHYSIOLOGY

EXCEED THE SPACE PROVIDED. There is a need to develop researchers who can identity and approach problems in biology and physiology trom a quantitative, integrative (across biological length scales), and systems perspective. This proposal aims to fill this need by establishing an interdisciplinary Pre-doctoral training program addressing the Systems and Integrative Biology area that will be housed in biomedicalengineering (BME). Our TrainingProgram in Quantitative Biology and Physiology will produce biomedical scientists who understand molecularbiology, cell biology andphysiology simultaneously with a strong technical background to approach biological and physiological problems from a quantitative perspective. We will emphasize quantitative and mathematical modeling techniques that are mechanistic, structurally based, and often ubiquitous across biological scale. Our graduates will acquire the requisite skills, breadth, and experience to branch at all levels (molecular, cell-tissue, organ, complex biodynamics) of a biological or physiological system or process. Our program represents a special opportunity to unite three departments at Boston University: Biomedical Engineering, Biology, and Mathematics; four interdisciplinary research centers; and an interdisciplinary program in MolecularBiology, Cell Biology, and Biochemistry (MCBB). We will establish a curriculum for the trainingprogram that includes rigorous course and lab rotational exposure to: (a) quantitative molecular biology, cell biology, and physiology, and (b) engineering-based biology in four thematic areas: Molecular Biological and Genetic Engineering, Cellular and Tissue Biomechanics and Electrophysiology, Organ and Sensory Systems, and Complex Biodynamics. We will require trainees to conduct thesis research that is interdisciplinary, integrative, quantitative,and linked to experimental data. Finally, we will establish a unique identity for the Quantitative Systems Biomedical Scientists that participate in our program through several interactive components, including a Seminar Series in Quantitative Biology and Physiology, Student-Faculty Science-Curriculum Retreats, Monthly Dinners and Journal Clubs. In summary, our intent is to produce integrated, quantitative, and systems oriented biomedical scientists that will assume leadership positions in the life science communities of academic institutions (e.g., universities and teaching hospitals) and industry. PERFORMANCE SITE ========================================Section End===========================================

超过提供的空间。 有必要培养能够在生物学和生理学中识别和处理问题的研究人员，一种定量，综合性（跨生物长度尺度）和系统观点。该建议旨在通过建立跨学科的博士前培训计划来满足这一需求，该计划涉及将在Biomedical Enginering（BME）中安置的系统和综合生物学领域。我们在定量生物学和生理学方面的训练计划将产生生物医学科学家，他们同时了解分子生物学，细胞生物学和植物学，并具有强大的技术背景，从定量角度来解决生物学和生理问题。我们将强调定量和数学建模技术，这些技术是机械性的，结构上的，并且在生物规模上通常无处不在。我们的毕业生将获得生物学或生理系统或过程的各个级别（分子，细胞 - 组织，器官，复杂生物动力学）分支的必要技能，广度和经验。我们的计划代表了在波士顿大学团结三个系的特殊机会：生物医学工程，生物学和数学；四个跨学科研究中心；以及分子生物学，细胞生物学和生物化学（MCBB）的跨学科计划。 我们将为培训计划建立一个课程，其中包括严格的课程和实验室旋转暴露至：（a）定量分子生物学，细胞生物学和生理学，以及（b）在四个主题领域的基于工程的生物学：分子生物学和基因工程，细胞和组织生物学和电子机械学和电学物理学系统和复杂系统，以及复杂的系统和敏锐的生物学系统和复杂的生物学系统，以及复杂的生物学系统和复杂的生物学系统，以及。我们将要求学员进行跨学科，综合性，定量并与实验数据相关的论文研究。最后，我们将为定量系统的生物医学科学家建立独特的身份，该科学家通过几个互动组件参与我们的计划，包括定量生物学和生理学的研讨会系列，学生 - 学生科学科学课程撤退，每月晚餐和期刊俱乐部。总而言之，我们的目的是生产综合，定量和系统的生物医学科学家，这些科学家将在学术机构（例如大学和教学医院）和行业的生活科学社区中担任领导地位。表演站点=============================================================================================