Integrating HIV/STI Prevention/Treatment in China

中国艾滋病毒/性传播感染的综合预防/治疗

• 批准号: 7004979
• 负责人: Thomas J. Coates
• 金额: $ 53.16万
• 依托单位: UNIVERSITY OF CALIFORNIA LOS ANGELES
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-09-09 至 2010-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7004979
• 关键词: AIDS education /prevention; AIDS therapy; China; HIV infections; behavioral /social science research tag; chlamydial disease; clinical research; communicable disease control; disease /disorder proneness /risk; education evaluation /planning; gonorrhea; health care personnel education; health care personnel performance; human subject; patient care; physicians; questionnaires; sex behavior; sexually transmitted diseases; training

We propose a five-year project (Integrating HIV/STI Prevention/Treatment in China) entitled "Ai Shi Zi" (pronounced "aces"), which in Mandarin simultaneously means "AIDS Plus" and also high-quality medical professional services for HIV infection. The goal is to teach physicians how to enhance and integrate prevention and care for HIV and STIs. HIV and STIs are intimately linked, and HIV and STI prevention requires both state-of-the-art treatment and changes in sexual behavior. A total of 60 counties have been recruited for the study and they will be randomized to the intervention and delayed-intervention control conditions. We hypothesize that patients of county-level physicians trained by us (primary training level) will have lower annual incidence of chlamydia and gonorrhea than patients of wait-list control physicians. For the primary level training (Aims 1 and 2), a total of 4 county-level hospital physicians from each county will be recruited to participate in the study (240 physicians in all). All physicians will be administered the baseline questionnaire. Physicians in intervention counties (n =120) will be provided with the experimental training, while physicians in the delayed-intervention control counties (n = 120) will receive the intervention following the final 12-month assessment. All intervention and delayed-intervention control physicians will be assessed post-training, and at 6 and 12 months following baseline (Aim 1). To assess these physicians' impact on patient care and behavior, 4 HIV- or STI- infected patients from each of the intervention and delayed-intervention control physicians (960 patients in all) will be assessed immediately following physician training and at 6 and 12 months following baseline (Aim 2). County-level physicians will each provide training to four township level physicians (secondary training) in a train-the-trainer model. For the secondary level training (Aims 3 and 4), township level physicians in the delayed-intervention control condition will be assessed at the same time points as the township-level intervention physicians-at baseline and 6 and 12 months following baseline (Aim 3). A total of 4 HIV or STI-infected patients for each township-level physician (3,840 patients total) will be assessed at baseline and at 6 and 12 months following baseline (Aim 4). We hypothesize that patients of township level physicians will have lower annual incidence of gonorrhea and Chlamydia than patients of waitlist control physicians. Public health impact: This project has the potential to provide a replicable and widespread training program to teach physicians to integrate HIV and STI prevention and care. If efficacious, it can be adopted by the Chinese government, and adapted for use in other countries.

我们提出了一个为期五年的项目（在中国整合艾滋病毒/STI预防/治疗），标题为“ Ai Shi Zi”（发音为“ ACES”），该项目同时表示“ AIDS Plus”以及HIV感染的高质量医疗专业服务。目的是教医生如何增强和整合对艾滋病毒和性传播感染的预防和护理。艾滋病毒和性传播疾病密切相关，艾滋病毒和性传播感染预防需要最新的治疗和性行为的变化。该研究总共已招募60个县，它们将被随机分配给干预措施和延迟干预控制条件。我们假设，与等待名单对照医生的患者相比，受我们培训的县级医生（初级培训水平）的患者的衣原体和淋病患者的年龄较低。对于初级培训（AIM 1和2），将招募来自每个县的4名县级医院医生参加该研究（总共有240位医生）。所有医师将被管理基线问卷。干预县的医师（n = 120）将接受实验培训，而延迟干预控制县的医生（n = 120）将在最后12个月评估后接受干预。在培训后以及基线后的6和12个月后，将评估所有干预和延迟干预控制医师（AIM 1）。为了评估这些医生对患者护理和行为的影响，将在医师培训后，在基线后的6和12个月后立即评估4例干预措施和延迟干预对照医生的4例HIV或受感染患者（总共960名患者）（AIM 2）。县级医师将分别为火车训练模型的四个乡镇医师（二级培训）提供培训。对于二级培训（目标3和4），将在延迟干预控制条件下的乡镇医师在基准时与乡镇级干预医师和基线后6和12个月的同一时间进行评估（AIM 3）。每位乡镇级医师总共4例HIV或STI感染患者（总计3,840名患者）将在基线时和基线后的6和12个月进行评估（AIM 4）。我们假设，乡镇医师的患者的淋病和衣原体的年发病率要比候补名单对照医生的患者较低。公共卫生影响：该项目有可能提供一项可复制和广泛的培训计划，以教医生整合艾滋病毒和STI预防和护理。如果有效的话，它可以被中国政府采用，并适用于其他国家。