Long-Term Mental Health Consequences of Chornobyl

切尔诺贝利事故对心理健康的长期影响

• 批准号: 6865655
• 负责人: EVELYN J BROMET
• 金额: $ 52.98万
• 依托单位: STATE UNIVERSITY NEW YORK STONY BROOK
• 依托单位国家: 美国
• 财政年份: 1995
• 资助国家: 美国
• 起止时间: 1995-09-30 至 2008-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6865655
• 关键词: Commonwealth of Independent States; adolescence (12-20); age difference; angers; anxiety disorders; behavioral /social science research tag; belief; child psychology; clinical research; disasters; energy source; fear; gender difference; human subject; interview; locus of control; longitudinal human study; major depression; mental health epidemiology; outcomes research; parents; posttraumatic stress disorder; psychosomatic disorders; quality of life; questionnaires; radiation

DESCRIPTION (provided by applicant): This competing renewal of MH51947 seeks to examine the long-term well-being of a cohort of mothers and children in Kyiv, Ukraine, first interviewed in 1997, 11 years after the Chornobyl accident. The proposed follow-up field work will be conducted in 2004-05. Our 1997 study focused on children born between 2/1/85 -1/31/87 to families evacuated to Kyiv from the contaminated region around Chornobyl. The control group was composed of gender matched classmates and their mothers. The 1997 results showed that compared with controls, the evacuee mothers reported more health problems in their children, had more anxiety, depressive, somatic, and post-traumatic stress symptoms, and were more concerned about their health and their family's health because of the Chornobyl accident. At that time, there were few differences in the medical evaluations or self-reported well-being of the evacuee children, who were 10-12 years old, compared to classmate controls. We propose to extend our original study by reevaluating the cohort with the CIDI and other measures when the children are age approximately 18, i.e., when depressive, anxiety, and substance disorders emerge, and by including physical examinations and blood tests. This cohort is the highest risk group for thyroid cancer and thus the focus of increased societal concern. To redress the limitation of having only Kyiv controls, the study will be expanded to include population-based controls selected from participants in the national co-morbidity survey of Ukraine conducted in 2002 (MH61905) who are the same age as the evacuee children and live in areas uncontaminated by radiation. The response rate for the original study was close to 90%, and we anticipate a better than 90% follow-up rate because of the residential stability of the sample. The analysis will focus on a set of specific hypotheses, including the prediction that both groups of Kyiv children and mothers will be more symptomatic at follow-up, and that the evacuee teens will report significantly more somatic and psychological symptoms and Chornobyl-related anxiety and will have higher rates of affective, anxiety, and substance use disorders than classmate controls. We further predict that the Kyiv control mothers and children will be more symptomatic and fearful about Chornobyl than the population-based controls. In light of current events, the opportunity to further our understanding of responses to prolonged threat to health is a key strength.

描述（由申请人提供）： MH51947的这种竞争续约旨在研究乌克兰基辅的一群母亲和儿童的长期福祉，在1997年首次接受了Chornobyl事故后11年的采访。拟议的后续现场工作将于2004 - 05年进行。我们的1997年研究重点是在2/1/85 -1/31/87之间出生的儿童，向基辅从Chornobyl周围受污染地区撤离的家庭。对照组由性别匹配的同学及其母亲组成。 1997年的结果表明，与对照组相比，撤离母亲报告了孩子更多的健康问题，患有更多的焦虑，抑郁，体细胞和创伤后压力症状，并且由于Chornobyl事故而更加关注他们的健康和家人的健康。当时，与同学对照组相比，撤离儿童的医学评估或自我报告的福祉几乎没有差异。我们建议通过重新评估与CIDI和其他措施的队列来扩展我们的原始研究，当时儿童大约18岁，即抑郁，焦虑和药物疾病出现，以及包括身体检查和血液检查和血液检查。该队列是甲状腺癌的最高风险群体，因此是增加社会关注的重点。为了纠正仅拥有KYIV控制的局限性，该研究将扩展到包括从2002年进行的乌克兰（MH61905）的国家合并症调查中选择的基于人群的控制，这些调查与疏散儿童的年龄相同，并生活在未经辐射的地区。 原始研究的回应率接近90％，由于样品的住宅稳定性，我们预计将超过90％的随访率。该分析将集中在一组特定的假设上，包括预测，基辅儿童和母亲在随访时都会更有症状，并且撤离疏散的青少年将报告明显更大的症状和心理症状，以及与Chornobyl相关的焦虑症，并且具有更高的情感，焦虑症，焦虑和物质使用障碍率比Classmate Contranters更高。我们进一步预测，基辅对照母亲和儿童将对Chornobyl更有症状和恐惧，而不是基于人群的对照。鉴于当前事件，有机会进一步理解对长期威胁对健康的反应的理解是一个关键优势。