Oxide Glass Fiber Optimized for Short Pulse IR Lasers

针对短脉冲红外激光器优化的氧化物玻璃光纤

• 批准号: 6443577
• 负责人: DANH C TRAN
• 金额: $ 12.24万
• 依托单位: INFRARED FIBER SYSTEMS, INC.
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-05-01 至 2003-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6443577
• 关键词: biomedical equipment development; fiber optics; germanium; infrared radiation; laser therapy; lasers; oxides; technology /technique development

There is a clinical need for optimized optical fiber transmission of short pulse mid-infrared laser radiation for surgical laser applications. Large potential medical markets such as cosmetic skin resurfacing, dentistry, and ophthalmology utilize the Er: YAG and Er:YSGG lasers for therapeutic procedures. The goal of this Phase I study is to further develop the germanium oxide glass fibers made by IFS so that they may be used in these applications. There are three aims of this study: (1) Testing and development of fibers using a short-pulse ER:YAG laser for potential ophthalmic applications requiring further precision, (2) Testing at high-power, high pulse repetition rates for dental and cosmetic applications requiring rapid removal of large amounts of tissue, and (3) development of more compatible germanium oxide fibers. Further Phase II work will be done on the continued fiber development and the development of specialized fiber probe tip designs for flexible delivery of laser radiation during custom surgical laser procedures. PROPOSED COMMERCIAL APPLICATIONS: IR fiber able to deliver laser energy from short pulse mid-infrared lasers would have many applications in laser surgery and dentistry, including ophthalmology and dermatology, for example.

临床上需要优化用于手术激光应用的短脉冲中红外激光辐射的光纤传输。美容换肤、牙科和眼科等潜在的巨大医疗市场利用 Er: YAG 和 Er:YSGG 激光器进行治疗。第一阶段研究的目标是进一步开发 IFS 制造的氧化锗玻璃纤维，以便将其用于这些应用。这项研究有三个目标：(1) 使用短脉冲 ER:YAG 激光器测试和开发光纤，用于需要更高精度的潜在眼科应用，(2) 在牙科和美容领域进行高功率、高脉冲重复率测试需要快速去除大量组织的应用，以及（3）开发更相容的氧化锗纤维。进一步的第二阶段工作将继续进行光纤开发和专门光纤探针尖端设计的开发，以便在定制外科激光手术期间灵活地传递激光辐射。拟议的商业应用：能够从短脉冲中红外激光器传输激光能量的红外光纤在激光手术和牙科领域有许多应用，例如眼科和皮肤科。

项目成果

Erbium:YAG laser lithotripsy using hybrid germanium/silica optical fibers.

使用混合锗/石英光纤进行铒：YAG 激光碎石术。

• 发表时间: 2004-11
• 影响因子: 2.7
• 作者: Yang, Yubing;Chaney, Charles A;Fried, Nathaniel M
• 通讯作者: Fried, Nathaniel M

Optimization of the Erbium:YAG laser for precise incision of ureteral and urethral tissues: in vitro and in vivo results.

优化铒:YAG 激光精确切割输尿管和尿道组织：体外和体内结果。

• 发表时间: 2003
• 作者: Fried, Nathaniel M;Tesfaye, Zelalem;Ong, Albert M;Rha, Koon H;Hejazi, Pooya
• 通讯作者: Hejazi, Pooya

Hybrid germanium/silica optical fibers for endoscopic delivery of erbium:YAG laser radiation.

用于内窥镜传输铒：YAG 激光辐射的混合锗/石英光纤。

• 发表时间: 2004
• 作者: Chaney, Charles A;Yang, Yubing;Fried, Nathaniel M
• 通讯作者: Fried, Nathaniel M