GRC on Second Messengers & Protein Phosphorylation

GRC 关于第二信使

• 批准号: 6748197
• 负责人: Morris Jay Birnbaum
• 金额: $ 0.5万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-06-01 至 2006-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6748197
• 关键词: biological signal transduction; cardiovascular disorder; cardiovascular system; cell biology; cell differentiation; cell growth regulation; meeting /conference /symposium; neoplasm /cancer; phosphorylation; second messengers; travel

DESCRIPTION (provided by applicant): We are requesting partial support for operation of the Gordon Research Conference (GRC) on Second Messengers and Protein Phosphorylation, which has been held annually since the early 70's. Over the years this GRC has been the venue where research leading to several Nobel Prizes was first presented. The meeting is held annually at Kimball Union Academy in Meriden, New Hampshire, which provides a familiar and handicapped-accessible venue to promote open interaction among participants. The 2003 iteration of this GRC will begin on Sunday night June 8 and conclude on Thursday evening June 12. The conference focuses on signal transduction mechanisms that regulate cell growth, differentiation, survival and metabolism. A full understanding of these signaling mechanisms is scientifically and clinically important because their failure plays a direct role in contemporary health problems that affect millions of people worldwide, such as diabetes, obesity, aging, cancer, cardiovascular disease, neurodegeneration, and developmental disorders. The speakers are encouraged to integrate biochemical, structural, cell biological and genomic approaches that provide a comprehensive understanding of the molecular aspects of signaling mechanisms as they relate to disease. The plenary speaker has been selected to set the stage for the conference and to challenge the participants to think about signal transduction from novel perspectives. The conference will consist of 8 sessions, each with a discussion leader and four speakers, selected from investigators who have made important recent contributions. At least 20% of the speakers are women or members of minority groups. Speakers in each session will develop the structure and function of important paradigms in signal transduction and relate these systems to disease mechanisms and potential treatment strategies. The co-chairs will select 135 participants from applicants, including representatives from industry and academia, senior scientists, postdoctoral fellows and graduate students. A special effort will be made to recruit minority participants by a direct mailing program. Participants will be encouraged to present posters on new and interesting results each afternoon. Importantly, the conference provides a forum for young investigators to see the connection between fundamental scientific inquiry and the application of scientific methods to the design of efficacious interventions for human disease. To emphasize this goal, four poster presentations that complement the themes of the meeting will be selected for brief oral presentation during the main sessions.

描述（由申请人提供）：我们要求对戈登研究会议（GRC）在第二季度和蛋白质磷酸化方面的运营进行部分支持，该会议及其蛋白质磷酸化是自70年代初以来每年举行的。 多年来，这个GRC一直是首次提出诺贝尔奖的研究场所。 该会议每年在新罕布什尔州梅里登的Kimball Union Academy举行，该学院提供了一个熟悉且障碍的场地，以促进参与者之间的公开互动。 该GRC的2003年迭代将于6月8日星期日开始，并于6月12日星期四结束。会议重点介绍了调节细胞生长，分化，生存和代谢的信号转导机制。 对这些信号机制的充分理解在科学和临床上很重要，因为它们的失败在影响全球数百万人的当代健康问题中起着直接作用，例如糖尿病，肥胖，衰老，癌症，癌症，心血管疾病，神经减退症和发育障碍。 鼓励说话者整合生化，结构，细胞生物学和基因组方法，这些方法对与疾病有关的信号机制的分子方面提供了全面的理解。 全体议长已被选为为会议奠定基础，并挑战参与者从新颖的角度考虑信号转导。 该会议将包括8个会议，每个会议都有一个讨论负责人和4位发言人，这些演讲者是从研究人员做出了重要贡献的调查人员中选出的。 至少有20％的演讲者是妇女或少数群体的成员。 每个会议中的说话者将发展重要范式在信号转导中的结构和功能，并将这些系统与疾病机制和潜在的治疗策略联系起来。 共同主席将从申请人中挑选135名参与者，包括工业和学术界的代表，高级科学家，博士后研究员和研究生。 通过直接邮寄计划招募少数群体参与者将做出特别的努力。 每天下午，将鼓励参与者以新有趣的结果介绍海报。 重要的是，该会议为年轻的研究人员提供了一个论坛，以查看基本科学探究与科学方法在设计人类疾病有效干预措施上的应用之间的联系。 为了强调这一目标，将在主要会议期间选择四个补充会议主题的海报演示文稿。