Infant and Child Neurotoxicity Studies:

婴儿和儿童神经毒性研究：

• 批准号: 6757081
• 负责人: Joan Marie Cranmer
• 金额: $ 4.9万
• 依托单位: UNIV OF ARKANSAS FOR MED SCIS
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-02-01 至 2005-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6757081
• 关键词: Hawaiian; child (0-11); disease /disorder etiology; environmental exposure; halobiphenyl /halotriphenyl compound; hazardous substances; infant human (0-1 year); longitudinal human study; meeting /conference /symposium; mercury poisoning; methylmercury; neurotoxicology; pediatrics; travel

DESCRIPTION (provided by applicant) The 21st International Neurotoxicology Conference (NTX XXI) will be held Feb. 10-14, 2004 at the Ala Moana hotel in Honolulu, Hawaii. NTX XXI will address the theme Infant and Child Neurotoxicity Studies: Subtle and Long-Term Effects. Studies will focus on methylmercury (MeHg), PCBs, heptachlor, other persistent pollutants and mixtures. The highlight of this conference is that all the major longitudinal children's studies addressing these important pollutants will be presented together for the first time! This will allow a unique opportunity to make significant advances in our understanding of the subtle and latent effects that these chemicals -alone or in combination-may be posing to our children. Justification for Hawaii Venue: Results of two major research efforts involving Hawaiians and others from the Pacific Rim will be presented for the first time at this conference. These two major themes require the meeting to be held on Oahu. The two areas are: (1) The Hawaii Heptachlor Study (20-yr study results) and (2) Persistent Pesticides and the Honolulu-Hawaii-Asia Aging Cohort. The Hawaii Heptachlor Research and Education Foundation promised Hawaiian citizens that the results of the Heptachlor Children's Study first would be reported to the Hawaiian community. The last day of the conference will be a "Report Back to the Community" in a Public Session devoted to the Hawaii Heptachlor Study 20 years after the initial pollution. Specific Aims: (1) To provide an internationally recognized, interdisciplinary scientific forum for presentation of the major longitudinal children's studies investigating the low-level, long-term effects of MeHg, PCBs, lead, heptachlor, other pesticides and mixtures. (2) To conduct an Open Public Forum/Town Meeting for clinical and basic scientists, clinicians and the citizens of Hawaii who were involved in the 20-year Heptachlor studies. To facilitate communication between the researchers, and the parents & children from Hawaii who were exposed to Heptachlor to discuss the implications of study results. (3) To convene scientists from different sectors to exchange data and theories regarding the etiology, mechanisms, diagnosis, treatment and prevention of environmentally-induced diseases or disorders of the nervous system in the fetus, infant, child, adolescent, and latent effects in the adult. To provide an established venue and ample time for informal scientific exchange to establish and promote collaborations and networking worldwide. (4) To encourage, mentor and recognize student researchers and young neurotoxicologists by offering pre-doctoral and post-doctoral awards (cash and plaques, travel scholarships, mentoring and networking opportunities. (5) To organize the keynote presentations, tutorials, invited and free presentations, discussions, demonstrations and interactions to document, major new research advances, facilitate identification of specific research gaps and potential experimental designs to answer questions. (6) To rapidly peer review and disseminate findings to the scientific community. The overall goal will be accomplished by organizing and conducting a five-day widely-advertised and well-organized conference according to the format of previous conferences in this well-established Neurotoxicology Conference series which has proven to be very successful. All presenters are invited to submit original research papers of new data presented and/or summaries of recent findings related to the specific topics in the Program. Papers will be peer-reviewed and rapidly published (less than one year) in Neurotoxicology, an international scientific journal that is widely disseminated, indexed, abstracted and available online.

描述（由申请人提供） 第21届国际神经毒理学会议（NTX XXI）将于2004年2月10日至14日在夏威夷檀香山的Ala Moana酒店举行。 NTX XXI将解决婴儿和儿童神经毒性研究的主题：微妙和长期影响。 研究将重点放在甲基汞（MEHG），PCB，七氯，其他持续污染物和混合物上。 这次会议的亮点是，所有针对这些重要污染物的纵向儿童研究将首次一起介绍！ 这将使我们有一个独特的机会在我们理解这些化学物质的微妙和潜在影响方面取得了重大进步，而这些化学物质或联合融合可能会为我们的孩子摆姿势。 夏威夷地点的理由：将首次在本次会议上提出两项涉及夏威夷人和其他夏威夷人的主要研究工作的结果。 这两个主要主题要求在瓦胡岛举行会议。 这两个领域是：（1）夏威夷七氯的研究（20年研究结果）和（2）持续的农药以及檀香山 - 霍瓦伊 - 亚洲老化人群。 夏威夷赫普特勒研究与教育基金会承诺，夏威夷公民首先将亨普勒儿童研究的结果报告给夏威夷社区。 会议的最后一天将是在最初污染后20年致力于夏威夷七赫勒研究的公开会议上的“回报社区的报告”。 具体目的：（1）提供一个国际认可的跨学科科学论坛，以介绍研究MEHG，PCBS，Lead，Lead，Heptachlor，Heptachlor，其他农药和混合物的低水平，长期影响的主要纵向儿童研究。 （2）为参与20年的亨普勒研究的临床和基础科学家，临床医生和夏威夷公民举行公开公共论坛/城镇会议。 为了促进研究人员与夏威夷的父母和孩子之间的沟通，他们暴露于亨氏勒，讨论研究结果的含义。 （3）召集不同部门的科学家来交换有关胎儿，婴儿，儿童，青少年和潜在影响的环境诱发疾病或神经系统疾病的病因，诊断，治疗和预防的研究和理论。 提供一个既定的场所和充足的时间进行非正式的科学交流，以建立和促进全球合作和网络。 (4) To encourage, mentor and recognize student researchers and young neurotoxicologists by offering pre-doctoral and post-doctoral awards (cash and plaques, travel scholarships, mentoring and networking opportunities. (5) To organize the keynote presentations, tutorials, invited and free presentations, discussions, demonstrations and interactions to document, major new research advances, facilitate identification of specific research gaps and potential experimental designs要回答（6），以迅速的同行审查并将整体目标传播给整体目标，并根据这一良好的神经毒性会议的序列来组织和井井有条的会议。程序中的主题。 论文将经过同行评审并迅速发表（不到一年）神经毒理学，这是一本国际科学杂志，广泛传播，索引，抽象和在线可用。