Nuclear Receptors: Steroid Sisters

核受体：类固醇姐妹

• 批准号: 6748025
• 负责人: Donald P McDonnell
• 金额: $ 0.6万
• 依托单位: KEYSTONE SYMPOSIA
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-04-01 至 2005-02-20
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6748025
• 关键词: meeting /conference /symposium; steroid hormone receptor; travel

DESCRIPTION (provided by applicant): The steroid hormone receptors are ligand-dependent intracellular transcription factors involved in a diverse array of physiological processes ranging from reproduction to lipid and mineral homeostasis. In addition, dysregulation of steroid receptor function has been implicated in the pathology of many diseases. The focus of this Keystone Meeting on Steroid Receptors will be on the mechanism of action of this class of transcriptional regulators. This meeting will incorporate lectures and extensive discussions on the latest advances in estrogen, progestin, glucocorticoid, mineralocorticoid, androgen and vitamin D receptor-mediated signal transduction. By emphasizing a class of receptors, rather than a disease state or a specific hormone, we believe that the goal of facilitating interactions between scientists with different backgrounds can best be achieved. The linking of this conference to its sister conference on orphan nuclear receptors reflects the organizers desire to assemble in one venue scientists who represent the full breadth of the nuclear receptor community. Using plenary, symposium and short talk formats together with extensive poster sessions we hope to spotlight the major advances that have occurred in this field over the past few years in a forum that will facilitate productive interactions between participating scientists.

描述（由申请人提供）：类固醇激素受体是配体依赖性的细胞内转录因子，参与了从繁殖到脂质和矿物质稳态的各种生理过程。此外，类固醇受体功能的失调与许多疾病的病理有关。这次基石会议上有关类固醇受体的重点将放在这类转录调节剂的作用机理上。这次会议将在雌激素，孕激素，糖皮质激素，矿物皮质激素，雄激素和维生素D受体介导的信号转导的最新进展中进行讲座和广泛的讨论。通过强调一类受体，而不是疾病状态或特定的激素，我们认为可以最好地实现促进具有不同背景的科学家之间相互作用的目标。这次会议与孤儿核受体的姐妹会议的联系反映了组织者渴望在一个代表核受体社区全部广度的场地科学家聚集的愿望。使用全体会议，研讨会和简短的脱口秀格式以及广泛的海报会议，我们希望焦点在过去几年中，在这个领域中发生的重大进展，这将促进参与科学家之间的富有成效互动。