The 10th International Xenopus Conference

第十届国际爪蟾会议

• 批准号: 6809474
• 负责人: JANET HEASMAN
• 金额: $ 1.5万
• 依托单位: CINCINNATI CHILDRENS HOSP MED CTR
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-09-14 至 2005-09-13
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6809474
• 关键词: Xenopus; biological models; functional /structural genomics; gene expression; gene targeting; information dissemination; meeting /conference /symposium; nucleic acid sequence; travel

DESCRIPTION (provided by applicant): The amphibian Xenopus provides a major model system for elucidating vertebrate cell and developmental biology. The large size of the embryo and its external development have facilitated biochemical, molecular, cellular, and developmental studies, providing important insights into the processes of oogenesis, fertilization, the cell cycle, cell signaling interactions, the cytoskeleton, cell movement, cell fate decisions, and patterning of the embryonic organ systems. In recent years, accelerated by the NIH genomic initiative, there has been a major increase in the availability of gene sequences in Xenopus, and it has become an organism of choice for studying gene function in cell biology and development. Continued rapid progress in these areas depends upon effective dissemination of novel findings to researchers in the field. This international biennial conference is the only regular meeting dedicated to the Xenopus model system. It will be held on September 14 to 17, 2004 at the Marine Biology Laboratory, Woods Hole, Massachusetts. Approximately 300 people will attend, representing all of the world's major Xenopus laboratories, including their investigators. The meeting's prime objective is to provide a forum for information exchange and interaction amongst Xenopus researchers. The meeting covers the full spectrum of Xenopus research areas, including the cancer-related topics of cell cycle control, stem cells and cell potency, as well as cell signaling and migration. Sessions include patterning of the early embryo as well as formation of the major organ systems, including the nervous, musculoskeletal, cardiovascular, renal and gastrointestinal systems. A major aspect will be to discuss on-going sequencing projects, novel methods of genomics and gene targeting, as well as gene expression profiling and databases.

描述（由申请人提供）：两栖动物提供了一个主要的模型系统，用于阐明脊椎动物细胞和发育生物学。 胚胎及其外部发育的大尺寸促进了生化，分子，细胞和发育研究，从而为卵子发生，受精，细胞周期，细胞信号相互作用，细胞骨架，细胞运动，细胞运动，细胞命运和胚胎器官系统的策略提供了重要的见解。 近年来，由NIH基因组倡议加速，Xenopus基因序列的可用性有了重大增加，并且它已成为研究细胞生物学和发育中基因功能的首选生物。 这些领域的持续快速进步取决于对该领域研究人员的新发现有效传播。 这次国际双年展会议是唯一致力于Xenopus模型系统的常规会议。 它将于2004年9月14日至17日在马萨诸塞州伍兹·霍尔（Woods Hole）的海洋生物学实验室举行。 大约有300人参加，代表包括其调查人员在内的世界上所有主要的Xenopus实验室。 会议的主要目标是为Xenopus研究人员之间的信息交流和互动提供一个论坛。 该会议涵盖了爪蟾研究区的全部范围，包括与癌症相关的细胞周期控制，干细胞和细胞效力的主题，以及细胞信号传导和迁移。 会议包括对早期胚胎的图案以及主要器官系统的形成，包括神经，肌肉骨骼，心血管，肾脏和胃肠道系统。 一个主要方面是讨论正在进行的测序项目，新颖的基因组学和基因靶向方法以及基因表达分析和数据库。