Neural Mechanisms in Casdiovascular Regulation

心血管调节的神经机制

基本信息

  • 批准号:
    6809097
  • 负责人:
  • 金额:
    $ 1.2万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2004
  • 资助国家:
    美国
  • 起止时间:
    2004-07-01 至 2005-06-30
  • 项目状态:
    已结题

项目摘要

DESCRIPTION (provided by applicant): The conference "Neural Mechanisms in Cardiovascular Regulation" is a long-running FASEB Summer Research Conference previously held in 1982, 1984, 1987, 1990, 1994, 1996, 1999 and 2002. The previous conferences have been well attended and their value recognized by leading investigators in the field. The topic is widely recognized as an important area of research. The nervous system plays a major role in regulation of arterial pressure, modulation of cardiac and renal function, and occurrence of syncope, cardiac arrhythmias and sudden death in pathologic states. The field is of interest to basic scientists interested in fundamental neural mechanisms, integrative physiologists, and clinical investigators interested in mechanisms of cardiovascular dysregulation in disease. This proposal for the FASEB Summer Conference 2004 will focus on understanding the central mechanisms involved in the physiological and pathological responses of the cardiovascular system to challenges from the external and internal environment. As articulated in 1932 by Walter B. Cannon in "The Wisdom of the Body", the ability of systems to adapt to environmental challenges and maintain homeostasis is fundamental to sustaining life. The scientific sessions for the 2004 FASEB "Neural Mechanisms in Cardiovascular Regulation" Summer Conference are tied together under the subtitle Environmental Challenges and Cardiovascular Regulation in Health and Disease. Each session will cover a specific external or internal environmental challenges and the responses of the neural mechanisms that are engaged to regulate cardiovascular function. Speakers for each session will span each topic from the identification of the challenge to human health to the understanding of the molecular and cellular mechanisms involved. Approximately 160 conference attendees will be selected from interested applicants. The conference will include 4 plenary sessions consisting of 2-3 presentations each, extended discussion sessions, and poster presentations. The plenary sessions include: 1) Osmotic Challenge and Body Fluid Regulation; 2) Steroid Hormone Challenges and Central Regulation of Cardiovascular Function; 3) Respiratory Challenges and Neural Control of the Circulation; and 4) Exercise Training, Temperature Stress and Neural Control of the Circulation. The majority of invited speakers have already agreed to participate and participation of young investigators will be encouraged. Time will be allotted for informal discussions and social interaction. Scientists from the United States and other countries, young investigators, and women are well represented in the program.
描述(由申请人提供): “心血管调节中的神经机制”会议是长期举办的 FASEB 夏季研究会议,曾于 1982 年、1984 年、1987 年、1990 年、1994 年、1996 年、1999 年和 2002 年举行。以前的会议出席人数众多,其价值得到了领导者的认可。实地调查人员。该主题被广泛认为是一个重要的研究领域。神经系统在调节动脉压、调节心肾功能以及病理状态下晕厥、心律失常和猝死的发生中发挥着重要作用。该领域引起了对基本神经机制感兴趣的基础科学家、对疾病中心血管失调机制感兴趣的综合生理学家和临床研究人员的兴趣。 2004 年 FASEB 夏季会议的这项提案将侧重于了解心血管系统对外部和内部环境挑战的生理和病理反应所涉及的核心机制。正如 Walter B. Cannon 于 1932 年在《身体的智慧》中所阐述的那样,系统适应环境挑战和维持体内平衡的能力是维持生命的基础。 2004 年 FASEB“心血管调节中的神经机制”夏季会议的科学会议以环境挑战和健康与疾病中的心血管调节为副标题。每个课程将涵盖特定的外部或内部环境挑战以及参与调节心血管功能的神经机制的反应。每场会议的演讲者将涵盖每个主题,从识别人类健康面临的挑战到理解所涉及的分子和细胞机制。将从感兴趣的申请者中选出大约 160 名与会者。会议将包括 4 场全体会议,每场包括 2-3 个演讲、扩展讨论会和海报展示。全体会议包括:1)渗透挑战和体液调节; 2)类固醇激素挑战和心血管功能的中枢调节; 3)呼吸挑战和循环的神经控制; 4) 运动训练、温度应激和循环的神经控制。大多数受邀演讲者已经同意参加,并将鼓励年轻研究者的参与。将分配时间进行非正式讨论和社交互动。来自美国和其他国家的科学家、年轻的研究人员和女性在该项目中都有很好的代表。

项目成果

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Meredith Hay其他文献

Meredith Hay的其他文献

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{{ truncateString('Meredith Hay', 18)}}的其他基金

GMP Manufacturing and IND Enabling Studies of Extended-Release PNA5: A Novel Therapeutic for Treating Cognitive Impairment in Patients at-risk for Alzheimer's Disease-Related Dementias and Vascular
缓释 PNA5 的 GMP 生产和 IND 启用研究:一种治疗阿尔茨海默氏病相关痴呆和血管性认知障碍患者认知障碍的新疗法
  • 批准号:
    10819329
  • 财政年份:
    2023
  • 资助金额:
    $ 1.2万
  • 项目类别:
PNA5: A Novel Mas Receptor Agonist for Treatment of Cognitive Impairment in Patients at Risk for Vascular Dementia and Alzheimer's Disease Related Dementia: an FDA required Toxicology Study
PNA5:一种新型 Mas 受体激动剂,用于治疗有血管性痴呆和阿尔茨海默氏病相关痴呆风险的患者的认知障碍:FDA 要求的毒理学研究
  • 批准号:
    10705874
  • 财政年份:
    2023
  • 资助金额:
    $ 1.2万
  • 项目类别:
Scale-up Manufacturing and IND Enabling Studies of Extended-Release Formulation of Mas Receptor Agonist for Treating Vascular Cognitive Impairment and Alzheimer's Disease-Related Dementias
用于治疗血管认知障碍和阿尔茨海默病相关痴呆的 Mas 受体激动剂缓释制剂的放大生产和 IND 启用研究
  • 批准号:
    10543390
  • 财政年份:
    2022
  • 资助金额:
    $ 1.2万
  • 项目类别:
Extended-Release Formulation of Mas Receptor Agonists as Novel Therapeutics for Treating Cognitive Impairment in Patients at-risk forAlzheimer's Disease-Related Dementias and Vascular Dementia
Mas 受体激动剂的缓释制剂作为治疗阿尔茨海默氏病相关痴呆和血管性痴呆风险患者认知障碍的新型疗法
  • 批准号:
    10594875
  • 财政年份:
    2022
  • 资助金额:
    $ 1.2万
  • 项目类别:
IND Enabling Studies for a Novel Mas Receptor Agonist for Treatment of Cognitive Impairment in Patients at Risk for Alzheimer's Disease Related Dementia
新型 Mas 受体激动剂的 IND 使研究能够治疗有阿尔茨海默病相关痴呆风险的患者的认知障碍
  • 批准号:
    10611383
  • 财政年份:
    2020
  • 资助金额:
    $ 1.2万
  • 项目类别:
IND Enabling Studies for a Novel Mas Receptor Agonist for Treatment of Cognitive Impairment in Patients at Risk for Alzheimer's Disease Related Dementia
新型 Mas 受体激动剂的 IND 使研究能够治疗有阿尔茨海默病相关痴呆风险的患者的认知障碍
  • 批准号:
    10609113
  • 财政年份:
    2020
  • 资助金额:
    $ 1.2万
  • 项目类别:
IND Enabling Studies for a Novel Mas Receptor Agonist for Treatment of Cognitive Impairment in Patients at Risk for Alzheimer's Disease Related Dementia
新型 Mas 受体激动剂的 IND 使研究能够治疗有阿尔茨海默病相关痴呆风险的患者的认知障碍
  • 批准号:
    10271099
  • 财政年份:
    2020
  • 资助金额:
    $ 1.2万
  • 项目类别:
IND Enabling Studies for a Novel Mas Receptor Agonist for Treatment of Cognitive Impairment in Patients at Risk for Alzheimer's Disease Related Dementia
新型 Mas 受体激动剂的 IND 使研究能够治疗有阿尔茨海默病相关痴呆风险的患者的认知障碍
  • 批准号:
    10378076
  • 财政年份:
    2020
  • 资助金额:
    $ 1.2万
  • 项目类别:
IND Enabling Studies for a Novel Mas Receptor Agonist for Treatment of Cognitive Impairment in Patients at Risk for Alzheimer's Disease Related Dementia
新型 Mas 受体激动剂的 IND 使研究能够治疗有阿尔茨海默病相关痴呆风险的患者的认知障碍
  • 批准号:
    10160326
  • 财政年份:
    2020
  • 资助金额:
    $ 1.2万
  • 项目类别:
IND Enabling Studies for a Novel Mas Receptor Agonist for Treatment of Cognitive Impairment in Patients at Risk for Alzheimer's Disease Related Dementia
新型 Mas 受体激动剂的 IND 使研究能够治疗有阿尔茨海默病相关痴呆风险的患者的认知障碍
  • 批准号:
    10437202
  • 财政年份:
    2020
  • 资助金额:
    $ 1.2万
  • 项目类别:

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