Center for Environment and Mammary Gland Development

环境与乳腺发育中心

• 批准号: 6805167
• 负责人: JOSE RUSSO
• 金额: $ 154.5万
• 依托单位: FOX CHASE CANCER CENTER
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-09-29 至 2010-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6805167
• 关键词: breast neoplasms; clinical research; cooperative study; environment related neoplasm /cancer; environmental exposure; human puberty; nutrition related neoplasm /cancer

The Fox Chase Cancer Center in Philadelphia, Pennsylvania, the University of Alabama Comprehensive Cancer Center in Birmingham, Alabama, and the Mount Sinai School of Medicine in New York, New York, have joined efforts for organizing a Breast Cancer and the Environment Research Center. Researchers at the three participating institutions have a long-lasting commitment to breast cancer research, demonstrated through pioneer work that has identified critical windows of susceptibility to carcinogenic and environmental exposures. The unique experience of this multi-institutional and multi-disciplinary group will provide a broad and comprehensive armarmentarium encompassing varied populations, clinical and basic sciences, and bioinformatics expertise that will be immediately translated to the population it will serve through carefully orchestrated programs under the guidance of patient advocates. The Breast Cancer and the Environment Research Center proposed here will be named Center for the Study of the Environment and Mammary Gland and Development. The Center is organized around two research projects, the Collaborative Project 1 (CP 1) and Collaborative Project 2 (CP 2), and two cores, the Administrative Core and the Community Outreach and Translation Core (COTC). The Administrative Core will serve as a liaison with the Steering Committee of the Breast Cancer and the Environment Research Center Consortium, the Breast Cancer and the Environment Task Force and the National Advisory Board. In addition, there will be an Executive Committee, which will be chaired by the Principal Investigator and will be integrated by the Co-Principal Investigators and one Cancer Advocate. The Executive Committee will receive advice from the Internal and the External Advisory Boards. The Executive Committee will meet on regular basis with the Co-PIs and investigators participating in CP 1 and CP 2, as well as with Members of the Administrative Core and the COTC. Consequently, the chain of authority for the Center grant will start from the Principal Investigator who will provide scientific leadership for all aspects of the Center. These lines of authority will not interfere with the internal chain of authority at each one of the participating institutions. The mission of the Center will be accomplished through interactive meetings among the participants of the Center, and other centers participating in this consortium.

宾夕法尼亚州费城的Fox Chase癌症中心，阿拉巴马州伯明翰的阿拉巴马大学综合癌症中心和纽约纽约纽约的西奈山医学院加入了组织乳腺癌和环境研究中心的努力。 三个参与机构的研究人员通过先驱工作证明了对乳腺癌研究的长期承诺，该研究已经确定了对致癌和环境暴露易感性的关键窗口。 这个多机构和多学科小组的独特经验将提供广泛而全面的武术群，包括各种人群，临床和基础科学以及生物信息学专业知识，并将立即将其转化为在患者倡导的指导下通过精心策划的计划来提供的人群。 这里提出的乳腺癌和环境研究中心将被任命为环境和乳腺研究中心。 该中心围绕两个研究项目组织，即协作项目1（CP 1）和协作项目2（CP 2），以及两个核心，即行政核心以及社区外展和翻译核心（COTC）。 行政核心将与乳腺癌指导委员会和环境研究中心财团，乳腺癌和环境特遣部队和国家顾问委员会联系起来。 此外，还将有一个执行委员会，该委员会将由首席调查员主持，并将由联合主管调查员和一名癌症倡导者整合。 执行委员会将获得内部和外部咨询委员会的建议。 执行委员会将定期与参与CP 1和CP 2的Co-Pis和调查人员开会，以及行政核心和COTC的成员。 因此，中心赠款的权力链将从主要研究人员开始，他们将为中心的各个方面提供科学领导。 这些权威路线不会干扰每个参与机构的内部权威链。 该中心的任务将通过中心参与者之间的互动会议以及参加该财团的其他中心来完成。