Appropriate Use of Oral Antibiotics in Children

儿童适当使用口服抗生素

• 批准号: 6707154
• 负责人: HOWARD BAUCHNER
• 金额: $ 14.24万
• 依托单位: BOSTON MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-01-01 至 2008-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6707154
• 关键词: antibiotics; chemotherapy; child (0-11); children; clinical research; ethnic group; human subject; human therapy evaluation; infant human (0-1 year); oral administration; otitis media; patient oriented research; therapy compliance

DESCRIPTION (provided by applicant): Howard Bauchner, M.D., Professor of Pediatrics and Public Health at Boston University School of Medicine (BUSM), is applying for a Midcareer Investigator Award in Patient-Oriented Research (K24). Dr. Bauchner completed his post-residency training as a Robert Wood Johnson Foundation General Pediatric Academic Fellow at Yale-New Haven in 1986. He joined the faculty at BUSM that year, was promoted to Associate Professor in 1990 and Professor in 1997. Dr. Bauchner's career has been committed to conducting patient-oriented research, and mentoring fellows and faculty in general pediatrics. His own research has focused on randomized controlled trials, methodologic reviews, and therapeutic trials in the areas of sleep, painful procedures, inappropriate oral antibiotic use, and iron deficiency anemia. He has published 60 peer-reviewed articles, and over the past five years conducted six studies in the area of inappropriate oral antibiotic use. Currently, with support from GlaxoSmithKline, he is beginning a practice-based research project in which 12 practices will be randomized to information about the appropriate antibiotics therapy or appropriate diagnosis of acute otitis media (AOM). In this study, it is estimated that 3600 children less than three years of age will be enrolled. The goal is to determine if children with AOM treated with appropriate antibiotics do better than children treated with inappropriate antibiotics. With support from the Maternal and Child Health Bureau, he is also conducting a randomized controlled trial that is focused on increasing the percentage of low-income and minority mothers who breastfeed their premature infants. In addition to his own research efforts, Dr. Bauchner is Project Director of an Institutional National Research Service Award and Faculty Development Program. With support from these two programs, four fellows have been in training each year for the past eight years. These fellows all require intensive mentoring and are conducting patient-oriented research. With support from this program, Dr. Bauchner will commit 50% effort to conducting patient-oriented research and mentoring. He will expand his mentoring efforts to include fellows and faculty in the Divisions of Pediatric Emergency Room Services, Child Development and Adolescent Medicine, and become a senior advisor to the CREST Program (K30) at BUSM.

描述（由申请人提供）：波士顿大学医学院（BUSM）的儿科和公共卫生教授霍华德·鲍赫纳（Howard Bauchner）申请了以患者为导向研究的中级护理研究者奖（K24）。 Bauchner博士于1986年在耶鲁 - 纽黑文（Yale-New Haven）的罗伯特·伍德·约翰逊基金会（Robert Wood Johnson Foundation）的一名罗伯特·伍德·约翰逊基金会（Robert Wood Johnson Foundation）的居住后培训完成。鲍赫纳（Bauchner）的职业生涯一直致力于进行以患者为导向的研究，并指导一般儿科的研究员和教师。他自己的研究集中在睡眠，痛苦的程序，不适当的口服抗生素使用以及缺铁性贫血领域的随机对照试验，方法论评论和治疗试验上。他已经发表了60篇经过同行评审的文章，在过去的五年中，他在口服抗生素使用不当的领域进行了六项研究。目前，在葛兰素史克（Glaxosmithkline）的支持下，他开始了一个基于实践的研究项目，其中12种实践将被随机分配到有关适当的抗生素疗法或适当诊断急性中性炎培养基（AOM）的信息。 在这项研究中，估计将招募3600名小于三岁的儿童。目的是确定接受适当抗生素治疗的儿童是否比接受不适当抗生素治疗的儿童更好。在孕产妇和儿童健康局的支持下，他还进行了一项随机对照试验，该试验的重点是增加母乳喂养其早产儿的低收入和少数族裔母亲的百分比。除了自己的研究工作外，Bauchner博士还是机构国家研究服务奖和教职发展计划的项目主管。在这两个计划的支持下，在过去八年中，每年有四名研究员进行培训。这些研究员都需要密集的指导，并正在进行以患者为导向的研究。在该计划的支持下，Bauchner博士将付出50％的努力来进行以患者为导向的研究和指导。他将扩大指导工作，以在小儿急诊室服务，儿童发展和青少年医学的部门中包括研究员和教职员工，并成为Busm的Crest计划（K30）的高级顾问。