Core--Statistics, Epidemiology, and Data Management

核心——统计学、流行病学和数据管理

• 批准号: 6736616
• 负责人: BRUCE LEVIN
• 金额: $ 26.83万
• 依托单位: NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-03-28 至 2008-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6736616
• 关键词: AIDS education /prevention; HIV infections; biomedical facility; computer data analysis; data collection methodology /evaluation; data management; disease /disorder proneness /risk; epidemiology; human data; information systems; statistical service /center; statistics /biometry

DESCRIPTION (provided by applicant): This is a revised application for the Statistics Epidemiology. and Data Management (SED) Core. The SED Core will advance HIV research and improve the quality of applications submitted by HIV Center-affiliated researchers by providing advice and assistance with state-of-the-art statistics, epidemiology, and data management. The Core will continue to serve as a center of excellence for the planning and design of investigator-initiated observational studies and behavioral interventions to reduce the risk of HIV infection on the individual, couple, group, and community levels. It will identify previously unrecognized statistical needs and study design improvements at the earliest planning stages in order to generate innovative solutions. The SED Core will meet the biostatistical, epidemiologic, and data management needs of Center-affiliated studies in a centralized and unified manner, consistent with modern principles of conduct of randomized controlled trials for behavioral intervention studies and observational methods for comparative or descriptive, nonexperimental studies. With its tripartite structure, the Core provides an interrelated network of talented specialists who are interdisciplinary and collaborate on all aspects of marshaling evidence: study design and instrumentation, anticipation and avoidance of bias, data management, statistical analysis and weighing of evidence, and interrelation with other disciplines to evaluate evidence and make causal inferences. The Statistics Component increases the likelihood that the randomized trials and observational studies will achieve their scientific goals through the application of good statistical principles and practices that minimize threats to validity. The biostatistical faculty and staff in the Core are highly experienced in collaborating with investigators in keeping studies on target and are pro-active in identifying and seeking resolutions to new statistical problems. The Epidemiology Component sits at the interface of the behavioral and biomedical sciences and thus is uniquely positioned to contribute to the articulation and refinement of research questions, to the selection of appropriate study designs, to the resolution of issues that arise in the field, and to the interpretation of the resulting data. The Data Management Component provides state-of-the-art management of research information, including forms production, ACASI instrumentation, and web-based research products. The integration of these skills and resources into one Core has led to a synergistic interaction of disciplines to identify and develop specific technical methods and products that will enhance the research productivity of the Center and support new and innovative research.

描述（由申请人提供）：这是统计流行病学的修订申请。和数据管理（SED）核心。 SED核心将通过提供有关最先进的统计，流行病学和数据管理的建议和帮助，提高HIV研究并提高艾滋病毒中心附属研究人员提交的申请质量。核心将继续作为研究人员提出的观察研究和行为干预措施计划和设计的卓越中心，以减少对个人，夫妇，团体和社区层面的艾滋病毒感染风险。它将在最早的计划阶段确定以前未认可的统计需求并研究设计改进，以生成创新的解决方案。 SED核心将以集中和统一的方式满足中心附属研究的生物统计学，流行病学和数据管理需求，这与现代的行为干预研究随机对照试验的原则一致 研究。核心提供了三方结构，提供了一个相互关联的才华横溢的网络 跨学科并在各个方面进行合作的专家：研究设计和仪器，预期和避免偏见，数据管理，统计分析和证据的权衡以及与其他学科的相互关系，以评估证据并做出因果推断。统计成分增加了随机试验和观察性研究将通过应用良好的统计原理和实践来最大程度地减少对有效性威胁的良好统计原则和实践来实现其科学目标的可能性。核心的生物统计学教职员工在与研究人员的合作方面非常有经验，以保持对目标的研究，并积极地识别和寻求解决新统计问题的决议。流行病学组成部分位于行为和生物医学科学的界面，因此，独特地定位于研究问题的表达和完善，以选择适当的研究 设计，解决现场出现的问题以及对结果数据的解释。 数据管理组件提供了研究信息的最新管理，包括表格生产，ACASI仪器和基于Web的研究产品。这些技能和资源融入一个核心已导致学科的协同互动，以识别和开发特定的技术方法和产品，以提高中心的研究生产力并支持新的和创新的研究。