Evidence-based Principles of Treatment

循证治疗原则

• 批准号: 6670118
• 负责人: FRANK S PEARSON
• 金额: $ 45.51万
• 依托单位: NATIONAL DEVELOPMENT AND RESEARCH INSTITUTES, INC.
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-07-10 至 2008-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6670118
• 关键词: age difference; alcoholism /alcohol abuse information system; clinical research; data collection methodology /evaluation; data management; data quality /integrity; drug abuse therapy; gender difference; human data; human therapy evaluation; meta analysis; outpatient care; rehabilitation; relapse /recurrence; residential care facility; age difference; alcoholism /alcohol abuse information system; clinical research; data collection methodology /evaluation; data management; data quality /integrity; drug abuse therapy; gender difference; human data; human therapy evaluation; meta analysis; outpatient care; rehabilitation; relapse /recurrence; residential care facility

DESCRIPTION (provided by applicant): NIDA has identified principles of effective treatment for substance abusers and the "Andrews Group" has identified principles of effective rehabilitative correctional treatment. Although there are individual studies to support the principles identified by NIDA for substance abusers and there are meta-analytic studies by the Andrews group on corrections-based treatment, no systematic review or meta-analysis of the full research literature has been conducted to verify principles of effective treatment for substance abusers. In previous studies, the research teams from NDRI and ISAP developed two meta-analytic databases containing hundreds of primary research studies of treatment for substance abusers, and these databases contain variables that can be used to test nine of the principles of treatment: six of the thirteen NIDA principles and all three of the Andrews group's principles. The primary aim of this study is to conduct a methodologically strong test of these nine principles. The method employed is systematic reviews and meta-analyses of the existing NDRI and ISAP meta-analytic databases, expanded to include recent studies to be collected for this project. An estimated total of 700 studies of treatment effectiveness will be available for meta-analyses. A secondary aim is to strengthen meta-analytic techniques and improve the methodological quality by (a) identifying sources of inconsistencies in meta-analyses conducted on the same topic and recommending improved protocols, (b) adapting and validating improved measures of the methodological quality of primary research studies, and (c) evaluating the use of different methods for dealing with missing data. The project has implications for practice as it will provide researchers and practitioners substantially more knowledge of (1) which principles of treatment are indeed effective in improving client outcomes, possibly under specific moderating factors (e.g., with specific types of clients), and (2) the scientific strength and limitations of meta-analysis using current protocols and how this essential method can be improved.

描述（由申请人提供）： NIDA已经确定了对滥用药物的有效治疗原则，“安德鲁斯组”已经确定了有效的康复矫正治疗原则。尽管有个人研究支持NIDA确定的滥用药物的原则，并且安德鲁斯小组对基于矫正的治疗进行了荟萃分析研究，但尚未对全面研究文献进行系统的审查或荟萃分析，以验证有效治疗物质的原理。在先前的研究中，来自NDRI和ISAP的研究团队开发了两个荟萃分析数据库，其中包含数百种对滥用物质的治疗的主要研究研究，这些数据库包含可用于测试治疗原理的变量：三十三个NIDA原理中的六个，以及安德鲁斯组的所有三个原理。这项研究的主要目的是对这9个原理进行方法论上的强烈测试。所采用的方法是对现有NDRI和ISAP元分析数据库的系统评价和荟萃分析，扩展到包括为该项目收集的最新研究。据估计，将为荟萃分析提供700项治疗效果研究。第二个目的是通过（a）确定对同一主题进行的荟萃分析的不一致来源来增强荟萃分析技术并提高方法论质量，并建议改进协议，（b）调整和验证改进的基本研究方法学质量的方法，以及评估不同方法的使用方法，以及（c）评估不同方法的使用。该项目对实践有影响，因为它将为研究人员和从业人员提供更多知识（1）哪些治疗原则确实有效地改善了客户的结果，可能是在特定的调节因素（例如，具有特定的客户类型）以及（2）使用当前协议以及这种基本方法的元分析的科学实力和局限性可以改善。