FLUORESCENCE SENSING OF CO2 & O2 IN BIOREACTOR

CO2 荧光传感

• 批准号: 6444719
• 负责人: GOVIND RAO
• 金额: $ 29.31万
• 依托单位: UNIVERSITY OF MARYLAND BALTIMORE
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-04-01 至 2002-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6444719
• 关键词: bioengineering /biomedical engineering; biological products; biomaterials; biomedical equipment development; biomedical resource; biotechnology; spectrometry

The rapid and accurate determination of physiological concentrations of biologicaly important gases like CO2 and O2 is an important factor in many clinical and bioprocess situations. The optical sensors based on phase fluorometry are developed as an alternative to electrode methodologies. A directly modulated infrared diode laser was frequency doubled in an intracavity KTP quasi-phase-matched wavequide, producing modulated laser light at 425 nm, which was subsequently employed for phase fluorometric detection of CO2 and O2 gases.

快速准确测定生理指标 CO2 和 O2 等生物重要气体的浓度 许多临床和生物过程情况中的重要因素。 这 基于相位荧光测定法的光学传感器被开发为 电极方法的替代方案。 直接调制红外线 二极管激光器在腔内 KTP 中倍频 准相位匹配波导，产生 425 调制激光 nm，随后用于相位荧光检测 CO2 和 O2 气体。