Sun Microsystems Sun Fire 6800 Server Supercomputer

Sun Microsystems Sun Fire 6800 服务器超级计算机

• 批准号: 6503258
• 负责人: JUDITH E. STENGER
• 金额: $ 115.8万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-06-15 至 2004-06-14
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6503258
• 关键词: biomedical equipment purchase; computer data analysis; computer network; data management; supercomputer

DESCRIPTION (provided by applicant): High Performance Computing (HPC) technology has been essential to many areas of biomedical research. The Center for Human Genetics (CHG) at Duke University Medical Center has been one of the leading groups in the mapping and identification of genes leading to human disease. Like others, our efforts have followed closely the technical advancements in computing and molecular biology that have occurred over the past 20 years. With the success of the Human Genome Project, whole new areas of investigation involving common, complex diseases are now possible. However, like the diseases under study, the analyses in these exciting areas of research are becoming increasingly complex. Specifically, as we develop new statistical methods for genetic analysis and expand our clinical and bioinformatics resources, we are at the stage where we require the speed and power of a multiprocessor midrange computer for the storage, analysis and visualization of our data. The huge amount of data now available requires the ability to pipe this data from database queries directly into computationally intensive analysis programs. However, because of the sensitive nature of patient data, exporting this data to external computer systems for analysis is fraught with security problems. Towards this end, we are requesting funds to purchase a SunMicrosystems SunFire 6800 featuring twenty-four 750Mhz processors, 72 GB memory and 3 terabytes of disk storage. This HPC will provide the database storage capacity and querying speed plus the computational processing capability needed to analyze our clinical, genotypic, and bioinformatics data.

描述（由申请人提供）：高性能计算 (HPC) 技术对于生物医学研究的许多领域至关重要。杜克大学医学中心人类遗传学中心 (CHG) 一直是绘制和鉴定导致人类疾病的基因的领先小组之一。与其他人一样，我们的努力密切关注过去 20 年来计算和分子生物学领域的技术进步。随着人类基因组计划的成功，涉及常见、复杂疾病的全新研究领域现在成为可能。然而，就像正在研究的疾病一样，这些令人兴奋的研究领域的分析正变得越来越复杂。具体来说，当我们开发用于遗传分析的新统计方法并扩展我们的临床和生物信息学资源时，我们正处于需要多处理器中端计算机的速度和功能来存储、分析和可视化数据的阶段。现在可用的大量数据需要能够将这些数据从数据库查询直接传输到计算密集型分析程序中。然而，由于患者数据的敏感性，将这些数据导出到外部计算机系统进行分析充满了安全问题。为此，我们请求资金购买 SunMicrosystems SunFire 6800，该计算机配备 24 个 750Mhz 处理器、72 GB 内存和 3 TB 磁盘存储。该 HPC 将提供数据库存储容量和查询速度以及分析临床、基因型和生物信息学数据所需的计算处理能力。