WOMEN AND INFANTS TRANSMISSION STUDY

妇女和婴儿传播研究

• 批准号: 6759398
• 负责人: CLEMENTE DIAZ
• 金额: $ 85.88万
• 依托单位: UNIVERSITY OF PUERTO RICO MED SCIENCES
• 依托单位国家: 美国
• 财政年份: 1993
• 资助国家: 美国
• 起止时间: 1993-07-01 至 2006-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6759398
• 关键词: AIDS education /prevention; AIDS therapy; HIV infections; Puerto Rico; antiviral agents; cooperative study; epidemiology; female; human pregnant subject; human subject; human therapy evaluation; infant human (0-1 year); patient oriented research; perinatal; pregnancy; pregnancy immunology; pregnancy infection; prenatal care; vertical transmission; women' s health

DESCRIPTION (provided by applicant): This is the renewal of the Women s and Infants Transmission Study at the University of Puerto Rico, Medical Sciences Campus. This application is for the fourth 5-year funding cycle. Accomplishments include the enrollment of the highest number of unique mother-infant pairs among the sites, the highest number of pregnant women and infants, the second highest number of deliveries, and a significant contribution of samples for the national or central WITS repository. Scientific accomplishments include the first comprehensive description of HIV disease progression in infants enrolled in the WITS; a consultative role in the CDC and PHS sponsored recommendations for the Prevention of Perinatal Transmission of HIV; CDC Disease Progression of Classification or staging for HIV infected infants; standardization and training of the neurological exam performed in WITS; and the reproductive choices of women enrolled in WITS. The WITS program in Puerto Rico has achieved a profound impact as a model program extended island wide for the prevention of perinatal transmission of HIV. Since September 1996 all infants born to women enrolled in the program have been free of HIV infection.

描述（由申请人提供）：这是妇女和 波多黎各大学医学科学的婴儿传播研究 校园。该申请适用于第四个五年资助周期。 成就包括注册最多数量的独特母婴 各站点中，孕妇数量最多， 婴儿，分娩数量第二高，并且有显着的 为国家或中央 WITS 存储库贡献样本。 科学成就包括首次全面描述艾滋病毒 参加 WITS 的婴儿的疾病进展；的咨询作用 疾病预防控制中心 (CDC) 和公共卫生服务部 (PHS) 提出了预防围产期疾病的建议 艾滋病毒的传播； CDC 疾病进展分类或分期 感染艾滋病毒的婴儿；神经系统检查的标准化和培训 在 WITS 中进行；以及加入 WITS 的女性的生育选择。 波多黎各的 WITS 项目作为典范产生了深远的影响 预防围产期传播的计划已扩展到全岛范围 艾滋病病毒。自 1996 年 9 月起，所有女性所生婴儿都参加了该计划 没有感染艾滋病毒。